Microfluidic pool structure for cell docking and rapid mixing.

A microfluidic pool structure for cell docking and rapid mixing is described. The pool structure is defined as a microchamber on one structural layer of a bilayer chip and connects with two or more individual microchannels on the other structural layer. In contrast to the turbulent flow in a macroscale pool, laminar streams enter and exit this microfluidic pool structure with definite and controllable direction that may be influenced by the location and geometry of the pool.

[Development of the chip system for measurement of red blood cell rheology].

We have developed a novel silicon microchannel system for the research of the red blood cell rheology and deformation. Recurring to many kinds of information technologies and advanced test means such as the electronic microscope, the image acquisition system and the computer processing system and by using the up-to-date Micro Electro Mechanical System (MEMS) technology, a new measuring system of red bood cell deformation is designed based on the chip and a model using the silicon microchannel to simulate capillary vessel network. It provides a real-time collection and anaysis of data which include image, speed, flow parameter, and so on.