[Effect of Huangqi decoction on delaying renal cell apoptosis induced by C ion irradiation in rats and its mechanism].

To investigate the molecular protective mechanisms of Huangqi decoction inhibiting the apoptosis of renal cells in the C radiation brain model rats. Fifty Wistar rats were randomly divided into five groups: normal control group, radiation alone model group, Huangqi decoction (high-dose, middle-dose and low-dose ) groups. The normal control group and the radiation alone group were treated with saline10 ml/(kg·d) by gavage, the Huangqi decoction treatment groups were treated with Huangqi decoction at the doses of 4.

[Intervention effect of Youguiwan on rats with knee osteoarthritis and its mechanism].

To study the effects of Youguiwan on the osteoglycin (OGN), osteonectin (ON), fibrinogen 2 (FBN2) of articular cartilage tissue in the model of knee osteoarthritis (KOA). Sixty SD rats were randomly divided into six groups: sham control group, model group, glucosamine sulfate group, Youguiwan (high-dose, middle-dose and low-dose )group. The modified Hulth method was used to establish KOA models for 6 weeks.

[Molecular Research of Acid-Generating Microbial Communities in Abandoned Ores in the Waste Dump of an Iron Mine in Anhui Province].

The waste dump of an iron mine in Anhui Province has been abandoned for several decades. Pyrite in the exposed waste ores is oxidized by acidophiles and large amounts of metal ions and HSO are released, resulting in the formation of an acid mine drainage (AMD) lake since 1970s. Besides the lake, there are also some small-scale AMD adjacent to the newly deposited waste ore.

[The therapeutic effects of Yougui pill on knee osteoarthritis and the expression of Wnt signal pathway related factors in rats].

Objectives: To observe the effects of Yougui pill (Traditional Chinese Medicine) on the related factors of Wnt signal pathway of rats with knee osteoarthritis (KOA), and explore its protective mechanism.

Methods: Sixty SPF SD rats were randomly divided into the sham-operative group, model group, glucosamine sulfate group, high-dose, middle-dose, low-dose of Yougui pill treated group (=10). KOA model was established by modified Hulth method for six weeks.

[The influence of benazepril and amlodipine on the expression of secretin and somatostatin in spontaneously hypertensive rats].

Objectives: Investigate the influence of benazepril and amlodipine on the expression of secretin (PZ) and somatostatin (SS) in spontaneously hypertensive rats (SHR).

Methods: Forty-five SHRs (14 weeks old, male) were randomly assigned into 3 groups (=15):SHR group, Benazepril group (which was given benazepril 0.90 mg·kg·d) and Amlodipine group (SHRs were given amlodipine 0.

Co-culture with lung cancer A549 cells promotes the proliferation and migration of mesenchymal stem cells derived from bone marrow.

The initiation and progression of various types of tumors, such as lung neoplasms, are driven by a population of cells with stem cell properties and their microenvironment. Bone marrow mesenchymal stem cells (BM-MSCs) in long-term culture may exhibit spontaneous changes in stem cell biological properties, including malignant transformations; however, the molecular mechanisms of this have not been fully elucidated. In the present study, a BM-MSC and lung cancer A549 cell co-culture system was utilized to investigate how the tumor microenvironment may spontaneously change the proliferation, migration and differentiation of BM-MSCs.

[The influences of ultrafiltration and alcohol sedimentation on protective effects of Radix Astragali and Radix Hedyseri against rat's cerebral ischemia].

Objective: To investigate the influences of ultrafiltration and alcohol sedimentation on protective effects of Radix Astragali and Radix Hedyseri against rat's cerebral ischemia.

Methods: Using dexamethasone (im.) and ligating common carotid artery, the rat stasis model combined transient cerebral ischemia was established to evaluate the effects of the ultrafiltration and alcohol sedimentation through detecting antioxidant system and other indexes in brain tissue.

[Effect of JTS caps. treating cerebral ischemia on metabolism and antioxidant system in cerebral ischemia rat].

Objective: To study the effects of JTS, Traditional Chinese Medicine caps. treating cerebral ischemia on metabolism and antioxidant system in cerebral ischemia rat.

Methods: I.

A screening strategy for phenotypic detection of carbapenemase in the clinical laboratory.

Nosocomial infections caused by carbapenemase-producing Enterobacteriaceae have emerged as an important challenge worldwide and represent a great limitation for antimicrobial therapy. Detection of carbapenemase in Enterobacteriaceae species also remains challenging. Although the modified Hodge test is recommended, it lacks specificity and is unable to distinguish between carbapenemase types.

Surgical management of radiation-induced temporal lobe necrosis in patients with nasopharyngeal carcinoma: report of 14 cases.

Background: Radiation-induced temporal lobe necrosis is a rare and serious late complication in irradiated patients with nasopharyngeal carcinoma (NPC). Treatment of radiation-induced temporal lobe necrosis with surgery has been seldom thoroughly investigated.

Methods: We retrospectively analyzed the clinical data of 14 patients with radiation-induced temporal lobe necrosis treated with surgical intervention.

[Imaging features and clinicopathological manifestations of solitary fibrous tumors].

Objective: To investigate the imaging features, clinical manifestations and pathological characteristics of solitary fibrous tumors (SFT).

Methods: The clinicopathological manifestations and medical imaging findings were analyzed retrospectively in 27 patients with surgically confirmed SFT.

Results: The SFTs originated from different parts of the body, including 18 in the chest, 4 in the abdomen, 1 in the lumboscral area, 3 in the pelvis, and 1 in the left shoulder.

[Correlation of multi-slice spiral CT features to clinicopathologic manifestations of gastrointestinal stromal tumor: a report of 49 cases].

Background And Objective: Gastrointestinal stromal tumor (GIST) is one of the most common mesenchymal tumors of the digestive system. Imaging examination plays an important role in preoperative diagnosis and postoperative evaluation for it. This study was to describe the multi-slice spiral computed tomographic (MSCT) findings and pathologic features of GIST, and to analyze their correlation.

[Comparison of CT findings between gastric cancer and gastric lymphoma].

Background & Objective: It is difficult to discriminate progressive gastric cancer and gastric lymphoma by CT imaging, because incrassate gastric wall, lump in gastric cavity, confined gastric cavity, intumescent lymph node, and distant metastasis can be displayed in both of them. This study was to compare the CT findings between gastric cancer and gastric lymphoma to improve diagnosis of gastric tumors, especially for gastric lymphoma.

Methods: CT images of 27 patients with pathologically proved progressive gastric cancer and 25 patients with pathologically proved gastric lymphoma were reviewed.

[CT features of parotid tumors: an analysis of 133 cases].

Background & Objective: Most parotid tumors grow slowly. It is difficult to evaluate their malignancy. This study was to analyze the CT features of parotid tumors.

[Malignant epithelial parotid tumors: CT imaging and histopathologic correlation].

Background & Objective: Malignant epithelial parotid tumors have various histopathologic types. Computed tomography (CT) has been widely used to detect parotid masses. This study was to analyze CT features of malignant epithelial parotid tumors to evaluate the diagnostic value of CT in the characterization of malignant epithelial parotid tumors.

[Gadolinium-loaded nanoparticle as a novel molecular imaging contrast agent for magnetic resonance imaging].

Objective: To synthesize a novel gadolinium-loaded nanoparticle as a molecular imaging contrast agent for magnetic resonance imaging.

Methods: Gadolinium ion was incorporated within a silica nanoparticle. The size of this nanosized particle was determined by using transmission electron microscope.

[Diagnostic values of CT perfusion imaging in pulmonary masses].

Background & Objective: Blood flow patterns with CT perfusion imaging (CTPI) had been innovated to delineate abnormal hemodynamic lesions in the liver, brain, and kidney. This study was to evaluate the blood flow patterns of pulmonary masses by CTPI, and determine the value of CTPI in differential diagnosis among benign, malignant, and inflammatory masses.

Methods: Fifty-two patients with previously diagnosed pulmonary masses (37 with malignant masses, 7 with benign masses, and 8 with inflammatory masses) underwent dynamic CTPI.

[Helical double-phase CT scan imaging features of hepatocellular carcinoma and pathology of false-positive lesions].

Background & Objective: The helical double-phase CT scan imaging features of hepatocellular carcinoma (HCC) overlap those of other hepatic lesions. This study was to investigate the helical double-phase CT scan imaging features of HCC to improve diagnosis accuracy.

Methods: Double-phase CT data and pathologic data of 52 HCC patients, received resection in Cancer Center of Sun Yat-sen University from Dec.

[CT diagnosis of various subtypes of ameloblastoma in the maxillomandibular region].

Background & Objective: Based on biological behavior and histopathologic characteristics, ameloblastomas in the maxillomandibular region can be divided into several subtypes with different prognosis. This study was to explore the clinical and CT imaging features of solid or multicystic ameloblastoma (SMA), unicystic ameloblastoma (UA), and malignant ameloblastoma (MA), and thus to improve the CT diagnostic accuracy for these diseases.

Methods: Clinical and CT features of 25 histologically proven ameloblastomas in the maxillomandibular region, including 14 SMAs, 6 UAs, and 5 MAs were analyzed retrospectively.