Publications by authors named "Yan-bin Ye"

The study aims to establish trimester-specific reference ranges for serum iodine (SI) in Chinese pregnant women and explore its associations with maternal and infantile thyroid function. Apparently healthy pregnant women were enrolled during their first antenatal visit. Fasting venous and spot urine samples were collected for determining serum and urinary iodine (UI) levels by a validated inductively coupled plasma mass spectrometry.

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This study aimed to explore the temporal associations between maternal serum iodine concentration (SIC) and common pregnancy outcomes in Chinese women. Eligible singleton pregnant women aged 20-34 years were selected, and their fasting blood samples were collected during early (T1, n = 1101) and mid-pregnancy (T2, n = 403) for SIC testing by inductively coupled plasma mass spectrometry. Multivariable linear regression indicated that logSIC at T1 (β = -0.

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Article Synopsis
  • A study aimed to investigate the relationship between dietary branched-chain amino acid (BCAA) intake and cardiovascular disease (CVD) risk among type 2 diabetes patients in China, as previous research had inconsistent findings.
  • The research included 419 type 2 diabetes patients, comparing those with CVD to those without, utilizing a food frequency questionnaire to assess dietary BCAA intake.
  • Results indicated that higher intake of total BCAA and individual amino acids like leucine significantly reduced the risk of CVD, with specific foods including whole grains and dairy contributing to this protective effect.
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  • The study aimed to translate and evaluate the Chinese versions of the ORTO-15 and ORTO-R scales to measure orthorexia nervosa (ON) risk, while also exploring related factors.
  • Two surveys were conducted to assess construct validity and reliability of the scales, with a total of 2,373 participants involved, averaging around 21 years old.
  • Findings indicated that the Chinese ORTO-R scale is a better screening tool for ON than ORTO-15, with physical activities and mental disorders linked to higher ON risk.
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The evidence regarding the impact of the scores on healthy eating indices on the risk of cardiovascular events among patients with type 2 diabetes (T2D) is limited. As such, in this study, we examined the associations of adherence to the Chinese and American dietary guidelines and the risk of cardiovascular disease (CVD) among Chinese individuals with T2D. We conducted a 1:1 age- and sex-matched case−control study based on a Chinese population.

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Background And Objective: soy protein and soy isoflavones have been suggested to be associated with improved cardiovascular risk factors (e.g., lipid profiles and uric acid (UA)), but few studies have been conducted among women with impaired glucose regulation (IGR).

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Objectives: Plant oil for cooking typically provides 40% to 50% of dietary fat, 65% of linoleic acid, 44% of α-linolenic acid and 41% of oleic acid in the Chinese diet. However, the comparative effects of fatty acids derived from plant oil on cardiovascular risk factors in Chinese are still inconclusive. Hence, the aim of this study is to investigate whether cardiovascular risk factors are altered depending on various types of plant oils such as peanut oil rich in oleic acid, corn oil rich in linoleic acid, and blend oil fortified by α-linolenic acid.

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Background: Previous studies have examined the role of the KQT-like subfamily Q member1 () gene polymorphisms on the risk of type 2 diabetes mellitus (T2DM), but the findings are inconclusive.

Objective: To examine the association between the gene polymorphisms and the risk of T2DM using an updated meta-analysis with an almost tripled number of studies.

Methods: Five electronic databases, such as PubMed and Embase, were searched thoroughly for relevant studies on the associations between seven most studied gene polymorphisms, including rs2237892, rs2237897, rs2237895, rs2283228, rs231362, rs151290, and rs2074196, and T2DM risk up to September 14, 2019.

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This cross-over experimental study aimed to examine the effects of filled chocolate consumption on blood glucose, insulin and ghrelin levels in 20 volunteers. After a one-week run-in period, study participants consumed two chocolate-based products, the tested biscuit or water for 21 days as a morning snack. After a two-week wash-out period, participants consumed another tested food for another 21 days.

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Previous studies have investigated the association between dietary inflammatory potential and the development of cancer. For breast cancer the results have been equivocal. The present study aimed to investigate whether higher Dietary Inflammatory IndexTM (DII) scores were associated with increased risk of breast cancer among Chinese women.

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Scope: This randomized, double-blind, and placebo-controlled trial evaluated the effect of isolated daidzein and genistein on glycemic control and insulin sensitivity in 165 Chinese women aged 30-70 with impaired glucose regulation (IGR).

Methods And Results: Participants were randomly assigned to one of three groups with a daily dose of 10 g of soy protein plus (i) no addition, (ii) 50 mg of daidzein, or (iii) 50 mg of genistein for 24 wk. Fasting glucose (FG), insulin, and glycosylated hemoglobin (HbA1c ), and glucose concentrations at 30, 60, 120, and 180 min and insulin concentrations at 30, 60, and 120 min after an oral 75-g glucose tolerance test were assessed at baseline and at 12 and 24 wk postintervention.

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Objective: Estrogen therapy is, to date, the most effective treatment of menopausal syndrome and also has a favorable effect on lipid profiles. Because of its potential adverse effects, however, a more acceptable alternative therapy needs to be identified. This study examines the effect of soy germ isoflavones on menopausal symptoms and serum lipids.

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Objective: To investigate the relationships between erythrocyte membrane n-6:n-3 PUFAs ratio and blood lipids and high sensitivity C-reactive protein (hs-CRP).

Methods: The observational study consisted of a population-based cross-sectional study of 456 Chinese and a subsequent 1-year follow-up study of 171 subjects with the fasting plasma total cholesterol of 5.13-8.

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Article Synopsis
  • The study aimed to analyze the levels of total polyphenols, flavonoids, and chlorogenic acid in Acer truncatum leaves throughout different months and their impact on fatty acid synthase (FAS) inhibition.
  • Using spectrophotometry, the researchers measured the chemical contents of the leaf extracts and assessed their inhibitory effects on FAS.
  • Findings indicated that while all leaves collected from May to November showed some inhibition, those from July had the highest polyphenol content and the strongest inhibitory effect on FAS, establishing a positive correlation between polyphenol levels and inhibitory efficacy.
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  • The study aims to improve the extraction process of polyphenols from Acer truncatum leaves that can inhibit fatty acid synthase using ethanol.
  • Researchers used a systematic approach (L16 orthogonal experiments) to test various factors including extraction time, temperature, solvent type, and solvent-to-raw material ratio.
  • The optimal extraction conditions were found to be 60% ethanol concentration, a solvent-to-raw material ratio of 1 g: 30 mL, and stirring for 1.5 hours at 50°C, leading to polyphenols with notable inhibitory effects on fatty acid synthase.
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Polyphenols, including flavonoids, are the major components of the extracts from aceraceous plants. They possess remarkable antibacterial and antitumour activity. Our study focused on whether the inhibition of the bacterial type II fatty acid synthesis system is the mechanism for the antibacterial effect of the related plant polyphenols.

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Many clinical studies have shown high-dose supplemental soy protein has beneficial effects on cardiovascular risk factors. We examined the association between habitual soyfood intake and carotid intima-media thickness (IMT) and plasma lipids in a cross-sectional study including 406 (M 134, F 272) middle-aged Chinese adults (40-65 years) without confirmed relevant diseases. We found significantly dose-respondent decreases in bifurcation IMT, total and LDL cholesterol associated with increased usual soyfood intake after adjusting for potential confounders (p for trend, all p<0.

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Background: Previous studies show that daily doses of 40-99 mg soy isoflavones produce inconsistent effects on preventing estrogen-related bone loss in postmenopausal women.

Aim Of The Study: To examined the bone-sparing effect of isoflavones at a higher dose in early Chinese postmenopausal women.

Methods: A total of 90 eligible women aged 45-60 years were randomly assigned to three treatment groups (30 subjects/group) with daily dosages of 0 (placebo), 84 and 126 mg isoflavones for 6 months.

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