Publications by authors named "Yan-Zhen Guo"

A kind of organosilicon intermediate was prepared using isophorone diisocyanate (IPDI), hydroxyl silicone oil (HSO), and hydroxyethyl acrylate (HEA). The organosilicon modification of epoxy resin was realized by introducing a -Si-O- group into the side chain of epoxy resin by chemical grafting. The effects of organosilicon modification of epoxy resin on the mechanical properties systematically discuss its heat resistance and micromorphology.

View Article and Find Full Text PDF

The discontinuous Galerkin spectral element method (DGSEM) is a compact and high-order method applicable to complex meshes. However, the aliasing errors in simulating under-resolved vortex flows and non-physical oscillations in simulating shock waves may lead to instability of the DGSEM. In this paper, an entropy-stable DGSEM (ESDGSEM) based on subcell limiting is proposed to improve the non-linear stability of the method.

View Article and Find Full Text PDF

This paper studies the energy stability property of the correction procedure via reconstruction (CPR) method with staggered flux points based on second-order subcell limiting. The CPR method with staggered flux points uses the Gauss point as the solution point, dividing flux points based on Gauss weights, with the flux points being one more point than the solution points. For subcell limiting, a shock indicator is used to detect troubled cells where discontinuities may exist.

View Article and Find Full Text PDF
Article Synopsis
  • Anlotinib, combined with paclitaxel and cisplatin, demonstrated promising efficacy as a first-line therapy for advanced esophageal squamous cell carcinoma (ESCC), showing significant anti-tumor activity.
  • In a phase II trial involving 47 patients, the median progression-free survival was 8.38 months, with an overall response rate of 76.1%, indicating a strong therapeutic effect of the drug combination.
  • Safety analysis revealed manageable side effects, primarily neutropenia and vomiting, with no treatment-related deaths; higher levels of the protein c-Kit were linked to improved patient outcomes.
View Article and Find Full Text PDF

Paeonia veitchii has been widely distributed in China under different ecological types. Its roots contain diverse phytochemical constituents, which possess very high bioactivities. However, the influence of ecological factors on activities and ingredients of P.

View Article and Find Full Text PDF

In last ten years, much attention focused on tree peony fruit (TPF) for edible oil production despite other potential utilization. The present study identified and quantified 29 bioactive components by liquid chromatography-electrospray ionization-triple quadrupole-mass spectrometry (LC-ESI-QqQ-MS) targeted approach during the development of TPF. Trans-resveratrol, benzoic acid, luteolin, and methyl gallate were selected as predominant chemical markers between seeds and pods through principal component analysis (PCA) and orthogonal partial least square-discriminant analysis (OPLS-DA).

View Article and Find Full Text PDF

Low miR-96-5p expression is characteristic of many cancers but its role in breast cancer (BCa) remains poorly defined. Here, the role of miR-96-5p in BC development was assessed. We demonstrate that exogenously expressing miR-96-5p inhibits the proliferative, migratory and invasive capacity of BCa cells.

View Article and Find Full Text PDF

Purpose: Postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) is a worrisome and life-threatening complication. This study aimed to investigate the risk factors and preventive strategies for POPF after PD.

Materials And Methods: We retrospectively reviewed 301 consecutive patients who underwent PD at our hospitals between January 2011 and December 2017.

View Article and Find Full Text PDF

Herbaceous peony has been widely cultivated in China due to its substantial ornamental and medicinal value. In the present study, the phenotypic characteristics, total fatty acid (FA) content, and nine FA compositions of herbaceous peony seeds from 14 populations belonging to six species and one subspecies were determined by normal test and gas chromatography/mass spectrometry (GC/MS). The results showed that the phenotypic characteristics of seeds varied dramatically among species.

View Article and Find Full Text PDF
Article Synopsis
  • Researchers developed a virtual reality system that simulates acupuncture at the Fengchi (GB 20) point, using data from experienced practitioners and force feedback devices.
  • This system allows acupuncture students to practice using a realistic 3D digital human model, which replicates the physical interactions of needles with human tissues.
  • The project aims to enhance acupuncture education by providing an immersive experience that integrates visual and tactile feedback, paving the way for future innovations in virtual acupuncture training.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to visually analyze the anatomy of Huantiao (GB 30) to enhance the safety and effectiveness of acupuncture needle insertion.
  • Using computer graphics technology, researchers created a 3-D model of the area around Huantiao (GB 30), including interactive tissue segmentation and nerve and blood vessel reconstruction.
  • The resulting animation realistically simulated the needle insertion process, providing insights into the anatomy that could improve clinical acupuncture practices.
View Article and Find Full Text PDF

Objective: To evaluate the clinical efficacy of FG for attaching conjunctival autografts in pterygium surgery.

Methods: Search was conducted in Pubmed, EMbase, Cochrane Library, CNKI, Wanfang database, CBM and VIP, and hand-search was also performed, the methodological quality were carried out according to evidence-based medicine (EBM). The qualities of the randomized controlled trials (RCT) were evaluated according to the Cochrane Handbook for Systematic Reviews of Interventions Version 5.

View Article and Find Full Text PDF

Objective: To study the effect of protein Nogo-66 on the expression of CD11b and MHC-II in retinal microglia of chronic ocular hypertension SD rats and the effects of protein Nogo-66 on the immunogenicity of injured retinal tissues.

Methods: It was a control experimental study. Chronic ocular hypertension rat model was established by laser photocoagulation on the anterior chamber angle and superficial vein of the sclera.

View Article and Find Full Text PDF

Objective: To investigate the intra-retinal expression of neuroglobin (Ngb) and death of retinal ganglion cells (RGCs) in acute retina ischemia rats.

Methods: It was an experimental study. The acute retina ischemia model was established by specific hypothesised left retina artery of Sprague-Dawley rats.

View Article and Find Full Text PDF
Article Synopsis
  • The study aims to enhance beginners' understanding of acupuncture at the Jianliao (TE 14) point by using a mechanical virtual reality setup that simulates surrounding tissues.
  • Researchers created a mathematical and mechanical model using VOXEL-MAN to visualize and interact with the virtual human's anatomical data.
  • The results showed that users could effectively experience the mechanical responses of acupuncture needle insertion through a force feedback device, improving their ability to learn and practice acupuncture techniques.
View Article and Find Full Text PDF

Objective: To study the expression of CD11b in the retinal microglia in laser induced ocular hypertension (OHT) SD rat.

Methods: It was an experimental study. OHT was induced by the coagulation of trabecular meshwork using 532-laser in sixty SD rats.

View Article and Find Full Text PDF

Objective: To display the Lung Meridian of Hand-Taiyin at the body surface in a virtual human.

Methods: After defining the acupoints as the control points, chose suitable function interpolation to compose skeleton curve, actualize surface rendering and to rebuild a tube-like meridian model.

Results: The rebuilt tubular meridian model had a good visual effect, and clearly showed different anatomic structures of the Lung Meridian of Hand-Taiyin.

View Article and Find Full Text PDF

By comparing and analyzing the similarity among the international scalp acupuncture, JIAO's scalp acupuncture and ZHU's scalp acupuncture, it is believed that the international scalp acupuncture is a combination of traditional acupuncture and other scalp acupuncture on the basis of channel theory of TCM, and this combination is worthy of discussion. However JIAO's scalp acupuncture lacks scientific evidence. So, the international scalp acupuncture following most contents of JIAO's scalp acupuncture is worthy of discussion.

View Article and Find Full Text PDF

This paper discusses the application of virtual reality technology in the 3-D visible human body and acupuncture research. Based on the 3-D visible human fused with the localization information and hierarchy of acupoints, the paper analyzes the force against the needle and haptic rendering during the needle manipulation according to the physical properties of different tissues. A haptic model is constructed to demonstrate the force behaviors during acupuncture, and the force will be produced and passed to the manipulator by a force feedback device.

View Article and Find Full Text PDF

Objective: To discuss the problem difficult to be presented for nerves and blood vessels in the 3D reconstruction of acupoints through studying 3D reconstruction of Jianliao (TE 14).

Methods: Muscles and other tissues were segmented by applying cointeractive segmentation method based on chromatic characteristic space; the nerve and blood vessels can be reconstructed by establishing mathematics model, and the needle-inserting animation of Jianliao (TE 14) could be obtained by running script file.

Results: During the course of 3D needle-inserting animation of Jianliao (TE 14), the spatial location between all kinds of tissues including the nerve and blood vessels and the needle body could be systematically observed.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to visually display the Meridian system on a simulated human body model.
  • Researchers used a combination of tube model-building and computer techniques, utilizing data from the Voxel-Man platform.
  • The results showed a successful visual representation of the Meridian lines, revealing various anatomical structures, indicating progress towards a comprehensive platform for Meridian research.
View Article and Find Full Text PDF

Objective: To study the effect of the electroacupuncture and Buyang Huanwu Decoction (BYHWD) on the regeneration of the rat's injured sciatic nerve.

Methods: Rat's sciatic nerve injury model was made by operation. The rats were treated with electroacupuncture or BYHWD and their nerve electro-physiological indices and histological changes tested by HRP were observed.

View Article and Find Full Text PDF