Establishment of a novel myocarditis mouse model based on cyclosporine A.

Background: Myocarditis is a myocardial injury that can easily cause adolescent death. Traditional research models of animal invasion with viral components, lipopolysaccharide (LPS) or porcine myocardial myosin, among others, have the shortcomings of potential biological safety hazards and high animal mortality.

Objective: To explore the construction of a novel myocarditis model with cyclosporine A and the potential genes and pathways associated with it.

Impacted molar upright with self-made helical spring.

With a case of mesial impaction of maxillary first and second molar, the mechanical analysis and clinical applications of a self-made helical spring for the uprighting treatment of mesial impacted molars was introduced.