Reciprocal regulation of LINC00941 and SOX2 promotes progression of esophageal squamous cell carcinoma.

LINC00941 is a novel long noncoding RNA (lncRNA) and emerging as an important factor in cancer development. However, the exact function and relative regulatory mechanism of LINC00941 in carcinogenesis of esophageal squamous cell carcinoma (ESCC) remain to be further clarified. The present study was to investigate the expression level, functions, and mechanisms of LINC00941 in ESCC tumorigenesis.

Multicomponent (Ce, Cu, Ni) oxides with cage and core-shell structures: tunable fabrication and enhanced CO oxidation activity.

Solvothermal synthesis of Cu2O cubes from Cu(OAc)2 in ethanol provided templates for tunable formation of novel multicomponent composites: hollow CeO2-Cu2O (), core-shell NiO@Cu2O () and hollow CeO2-NiO-Cu2O (). Composites catalyze the oxidation of CO at a lower temperature than the parent Cu2O cubes.

Analysis of the Baroreceptor and Vestibular Receptor Inputs in the Rostral Ventrolateral Medulla following Hypotension in Conscious Rats.

Input signals originating from baroreceptors and vestibular receptors are integrated in the rostral ventrolateral medulla (RVLM) to maintain blood pressure during postural movement. The contribution of baroreceptors and vestibular receptors in the maintenance of blood pressure following hypotension were quantitatively analyzed by measuring phosphorylated extracellular regulated protein kinase (pERK) expression and glutamate release in the RVLM. The expression of pERK and glutamate release in the RVLM were measured in conscious rats that had undergone bilateral labyrinthectomy (BL) and/or sinoaortic denervation (SAD) following hypotension induced by a sodium nitroprusside (SNP) infusion.

Comparative analysis of vestibular receptor and baroreceptor inputs to the nucleus tractus solitarius following acute hypotension in conscious rats.

Blood pressure is maintained by the interaction between the arterial baroreflexes and the vestibulo-cardiovascular reflexes during postural changes. In this study, the influence of the vestibular receptors on the maintenance of blood pressure following acute hypotension was quantitatively compared with the role of baroreceptors in terms of c-Fos protein expression in the nucleus tractus solitarius (NTS). Expression of c-Fos protein in the NTS was measured in conscious rats that had undergone bilateral labyrinthectomy (BL) and/or sinoaortic denervation (SAD).

Additive role of the vestibular end organ and baroreceptors on the regulation of blood pressure in rats.

Contribution of the vestibular end organ to regulation of arterial pressure was quantitatively compared with the role of baroreceptors in terms of baroreflex sensitivity and c-Fos protein expression in the rostral ventrolateral medulla (RVLM). Baroreflex sensitivity and c-Fos protein expression in the RVLM were measured in conscious rats that had undergone bilateral labyrinthectomy (BL) and/or baroreceptor unloading. BL attenuated baroreflex sensitivity during intravenous infusion of sodium nitroprusside (SNP), but did not significantly affect the sensitivity following infusion of phenylephrine (PE).

[Source apportionment of nitrogen and phosphorus from cropping non-point source pollution in Nansi Lake basin].

Field runoff pools were used to collect the field surface runoff samples of different cropping systems in Nansi Lake region, and different forms of nitrogen (N) and phosphorus (P) data were analyzed. The source profiles of N and P in different cropping systems were also obtained by summarizing the experimental data measured in the current study. Samples were also collected from the 11 main rivers of Nansi Lake basin and the concentrations of N and P were determined.

Elevated homocysteine and hypertension in Xinjiang Province, China.

Background: Few data are available comparing homocysteine (Hcy) levels in patients with hypertension in different ethnic groups.

Objectives: This study sought to determine whether there are associations of blood pressure and Hcy levels in patients with hypertension from Xinjiang Province, China.

Methods: We examined the serum total Hcy levels in a total of 451 Chinese of various ethnic groups (Han n=234 [51.