Publications by authors named "Yan-Yi Cen"
Objective: To compare negative expiratory pressure (NEP) technique with conventional test in detecting expiratory flow limitation (EFL) in chronic obstructive pulmonary diseases (COPD) patients.
Methods: EFL was measured with NEP technique and conventional method respectively in 72 COPD patients;EFL was measured with NEP technique in 20 COPD patients who failed to perform conventional test.
Results: EFL was detected in 54 of the 72 COPD patients.
Objective: To explore feasible and reliable methods for estnbolishment and of acute lung injury model in animal models.
Methods: Twenty-four healthy adult mongrel dogs with oleic acid-induced acute lung injury were evaluated for early-stage physiological response to acute lung injury using a balloon catheter system for measuring esophageal and gastric pressure.
Results: In canine models of early-stage oleic acid-induced acute lung injury that sustained spontaneous breathing, in terms of respiratory mechanics, some parameters obviously increased including the respiratory rate (RR), minute ventilation (VE), peak inspiratory volume (Vinsp, peak), mean inspiratory volume (VT/Ti), inspiratory airway resistance (Raw, insp) (P<0.
Objective: To evaluate the effects of different interventional strategies, namely controlled high-concentration oxygen therapy, continuous positive airway pressure (CPAP) and bi-level positive airway pressure (BiPAP) ventilation, on respiratory response and work of breathing (WOB) in canine models of early-stage acute lung injury (ALI).
Methods: After successful duplication of ALI models with oleic acid (diagnostic criteria: Pa(O2)/Fi(O2)