Serum adenosine deaminase activity and coronary artery disease: a retrospective case-control study based on 9929 participants.

Background: Adenosine deaminase (ADA) regulates purine metabolism through the conversion of adenosine to uric acid (UA). Adenosine and UA are closely associated with cardiovascular events, but the correlation between serum ADA activity and coronary artery disease (CAD) has not been defined.

Methods: We performed a hospital-based retrospective case-control study that included a total of 5212 patients with CAD and 4717 sex- and age-matched controls.

[Analysis of 4713 cases of Wuhan pesticide poisoning reports of year 2002 to 2010].

Objective: To provide scientific evidence of making measures for prevention of pesticide poisoning, the investigation on the condition of pesticides poisoning was carried out in Wuhan.

Methods: Registration data of pesticide poisoning from 2002 to 2010 in Wuhan were collected and statistically analyzed by SAS 9.1.

[A pilot study of selective screening for high risk children with inborn error of metabolism using tandem mass spectrometry in China].

Objective: The new technology of tandem mass spectrometry is exerting a significant impact on the diagnostics of inborn metabolic errors, and allows to detect a number of these disorders in a single step. The aim of the present study was to establish a dry blood filter paper method for amino acid and acylcarnitine profiles test using tandem mass spectrometry and to apply the method for selective screening in high risk children with inborn error of metabolism.

Method: The study group consisted of 104 high risk cases of inborn error of metabolism from 5 pediatric hospitals in Shanghai and Beijing were tested from November 2002 to June 2003; 77 were males and 27 females, the means age was 4.