Pure large cell neuroendocrine carcinoma originating from the endometrium: A case report.

Background: Large cell neuroendocrine carcinoma (LCNEC) of the endometrium is an uncommon and highly aggressive tumor that has not been comprehensively characterized. We report a case of pure endometrial LCNEC and review the current literature of similar cases to raise awareness of the histological features, treatment, and prognosis of this tumor.

Case Summary: We report the case of a 73-year-old woman who presented with irregular postmenopausal vaginal bleeding.