Publications by authors named "Yan-Mei Shi"

Neurotransmitters (NTs) are essential for intercellular communication and primarily include monoamine, amino acid, and cholinergic NTs. These molecules play important roles in the body's stress response, motor coordination, neuronal communication, and homeostatic functions. Previous studies have shown that abnormal changes in NT levels are associated with various neurological disorders.

View Article and Find Full Text PDF
Article Synopsis
  • A study evaluated the effectiveness and safety of the Chinese Medicine prescription "W-LHIT" for treating simple obesity in 37 patients, comparing it to a placebo in a double-blind trial over two months.
  • Results showed that 72.22% of the treatment group lost more than 5% of their body weight, significantly higher than the 36.84% in the placebo group, along with improvements in associated health conditions like hypertension.
  • The study concluded that W-LHIT appears to aid in weight loss and reduce obesity-related issues, likely due to changes in gut microbiota, without causing serious side effects or weight rebound.
View Article and Find Full Text PDF

Background: To systematically evaluate the quality of the guidelines for the diagnosis and treatment of Helicobacter pylori infection and to analyze the differences and reasons for the key recommendations in the guidelines.

Methods: Databases and websites were systematically searched to obtain guidelines for the diagnosis and treatment of Helicobacter pylori infection. Four independent reviewers used the Guideline Evaluation Tool (AGREE II) to evaluate the included guidelines.

View Article and Find Full Text PDF
Article Synopsis
  • The text analyzes the effectiveness of various animal models used to study atopic dermatitis (AD) in both traditional Chinese medicine (TCM) and Western medicine, highlighting how well these models reflect clinical symptoms.
  • It discusses the strengths and weaknesses of different modeling methods, noting that while some models are consistent with AD characteristics, they may be costly and not fully capture the disease’s progression.
  • The study suggests that integrating insights from both TCM and Western medicine could enhance the development of more accurate animal models for AD research.
View Article and Find Full Text PDF

Objectives: To fully assess the quality of the guidelines for the management of malignant pleural effusions (MPE) and ascites and reveal the heterogeneity of recommendations and possible reasons among guidelines.

Methods: A systematic search was performed in the database to obtain guidelines for the management of MPE and ascites. The AGREE IIGtool was used to assess the quality of these guidelines.

View Article and Find Full Text PDF
Article Synopsis
  • A study was conducted to compare the pharmacokinetics of five anthraquinones from Rheum palmatum L. in both normal and thrombotic focal cerebral ischemia (TFCI)-induced rats.
  • Plasma samples were analyzed using high-performance liquid chromatography-fluorescence, revealing that TFCI-induced rats had nearly double the levels of certain anthraquinones compared to normal rats, with significantly decreased clearance rates.
  • The findings indicate that these anthraquinones are quickly absorbed and slowly eliminated, providing insights that could improve the understanding of their efficacy and safety in clinical use.
View Article and Find Full Text PDF

A sensitive approach for the simultaneous determination of tilmicosin, erythromycin ethylsuccinate and clindamycin was developed by CE coupled with electrochemiluminescence detection with ionic liquid. The parameters for CE, electrochemiluminescence detection and the effect of ionic liquid were investigated systematically. The three analytes were well separated and detected within 8 min.

View Article and Find Full Text PDF

Human serum albumin (HSA) was the most abundant protein in human plasma and has significant physiological function. In Tris-HCl buffer solution (pH 7.4), water-soluble semiconductor CdSe quantum dots (QDs) reacted with HSA and the products resulted in a great enhancement of the intensity of resonance Rayleigh scattering (RRS) and second-order scattering (SOS).

View Article and Find Full Text PDF
Article Synopsis
  • A new method using capillary electrophoresis (CE) and electrochemiluminescence (ECL) has been developed to simultaneously detect enoxacin and ofloxacin.
  • The analysis can separate and identify these substances within 7 minutes, achieving very low detection thresholds and high precision.
  • This method was successfully applied to human urine, serum, and eye drop samples, providing valuable data for monitoring the pharmacokinetics of ofloxacin.
View Article and Find Full Text PDF

A sensitive method for simultaneous determination of azithromycin (AZI), acetylspiramycin (ACE), erythromycin (ERY), and josamycin (JOS) was developed by CE coupled with electrochemiluminescence detection with Ru(bpy)(3) (2+). The parameters related to separation and detection were investigated in detail. The four macrolides were well separated and detected within 6 min under the optimized conditions.

View Article and Find Full Text PDF

The main purpose of this study was to develop an inexpensive, simple, rapid and sensitive chemiluminescence (CL) method for the determination of glutamine (Gln) using a flow-injection (FI) system. Gln was found to strongly inhibit the CL signal of the luminol-H(2)O(2)-CuSO(4) system in Na(2)B(4)O(7) solution. A new FI-CL method was developed for the determination of Gln.

View Article and Find Full Text PDF

To provide the hard-won information on HIV-1 polymorphism from inmates in prison and to study the genetic variation of HIV-1 strains, we analyzed the characterization of the nucleotide and corresponding protein sequences of naturally occurring nef sequences derived from 16 HIV-1-positive inmates from prisons in China. Nested PCR and DNA sequencing were used to determine nef sequences in peripheral blood mononuclear cells. Phylogenetic analysis revealed a distribution of the viral sequences among subtype B, CRF_BC, and CRF_AE, with subtype B accounting for more than half of the genotypes.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionf7160f742mqe36hkd4thpsqr7gv1qlej): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once