Publications by authors named "Yan-Lai Hu"
Article Synopsis
- A study involving 52,047 pregnant women from 2012 to 2016 sought to investigate the link between high uterine artery pulsatility index (UtA-PI) values and the risk of congenital heart disease (CHD), looking at differences between singleton and multiple pregnancies.
- The research found that high right UtA-PI values were significantly associated with increased risks of maternal preeclampsia and, to a lesser extent, fetal CHD, especially in singleton pregnancies.
- Results indicated that preeclampsia mediated a significant portion of the CHD risk in singleton pregnancies, while high UtA-PI played a critical role in multiple pregnancies, highlighting the need for further research due to potential follow-up issues.
Axonal degeneration is a common pathological change of neurogenical disease which often arises before the neuron death. But it had not found any effective method to protect axon from degeneration. In this study we intended to confirm the protective effect of nicotinamide adenine dinucleotide (NAD), investigate the optimal administration dosage and time of NAD, and identify the relationship between silence signal regulating factor 1 (SIRT1) and axonal degeneration.
View Article and Find Full Text PDFTNF-α increases bone marrow mesenchymal stem cell migration to ischemic tissues.
Cell Biochem Biophys
April 2012
The objective of this study was to analyze the influence of TNF-α on rat mesenchymal stem cells (MSCs) and to assess feasibility of MSC transplantation to repair ischemic injury. In this study, adhesion molecules and cell specific surface markers on MSCs were measured after exposure to different concentrations of TNF-α. MSCs stimulated with varying concentrations of TNF-α were cultured with aortic endothelial cells, and the adhesion rate was measured.
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