Publications by authors named "Yan-Jia Li"

The golden snub-nosed monkey is one of the most endangered animal species endemic to China. In order to explore the characteristics and health risks of golden snub-nosed monkeys exposed to heavy metals, we collected the plant food sources, soil, and water samples from the golden snub-nosed monkey habitat in the Shennongjia Mountains; examined the contents of seven heavy metals (Cu, Zn, Pb, Cd, Cr, Ni, and As); and adopted the comprehensive pollution index, potential ecological risk index, and Nemerow index to evaluate pollutants in the water, soil, and food plants. At the same time, the Target Hazard Quotient method was used to assess heavy metals in the food plants.

View Article and Find Full Text PDF
Article Synopsis
  • Neuromyelitis Optica spectrum disorder (NMOSD) is a serious autoimmune disease affecting the central nervous system, and the best initial treatment options are still uncertain.
  • Researchers will conduct a clinical trial involving 430 NMOSD patients to assess the safety and efficacy of human umbilical cord mesenchymal stem cells (hUC-MSCs), looking for the optimal dosage.
  • This trial is significant as it aims to provide the first systematic evaluation of hUC-MSCs' clinical safety and effectiveness for NMOSD, potentially identifying the best treatment dose for patients.
View Article and Find Full Text PDF

Dingchuan decoction (DCD) is a traditional Chinese prescription for asthma that remains popular today. To systematically evaluate the effect of DCD on lung function, clinical effectiveness rate, and safety in children with asthma, significant databases were searched for randomized controlled trials from their inception to September 9, 2019. Randomized controlled trials assessing the effect of DCD on lung function and clinical effectiveness rate in children with asthma were included in this meta-analysis.

View Article and Find Full Text PDF

Atherosclerosis (AS) is the pathological basis of various vascular diseases and currently is seriously affecting human health. Numerous studies have paid more attention to natural medicines with anti-AS properties. As a traditional Uygur folk medicine, black mulberry fruits are conventionally used in the prevention and treatment of cardiovascular diseases in southern Xinjiang of China, and their underlying mechanisms remain unknown.

View Article and Find Full Text PDF

This study aimed to evaluate the diagnostic value of the modified hypertonic saline bronchial provocation test (HS-BPT) for children with asthma by using the high-power Aerosol Provocation System (APS). A total of 330 children suspected of having asthma and receiving HS-BPT-APS were included in this prospective survey conducted in Guangzhou, China from February 2017 to September 2018. The positive rate of HS-BPT-APS and the volume and types of adverse reactions were observed.

View Article and Find Full Text PDF

Solid-solution Li-ion cathode materials transform through a single-phase reaction thus leading to a long-term structural stability and improved cyclability. In this work, a two- to single-phase Li-extraction/insertion mechanism is studied through tuning the stoichiometry of transition-metal Fe/V cations to trigger a transition in the chemical reactivity path. Tavorite triclinic-structured LiFeVPOF (x = 0, 0.

View Article and Find Full Text PDF

Background: Familial progressive hyper- and hypopigmentation (FPHH) is a rare genodermatosis that is characterized by diffuse hyper- and hypopigmented spots on the skin and mucous membranes. It is caused by a pathogenic mutation of the KITLG gene.

Objectives: To investigate the clinical features and mutation of the KITLG gene in a Chinese family with FPHH.

View Article and Find Full Text PDF

Aim: To investigate the intervenient effect of compound traditional Chinese medicine on dendritic cells (DCs) in peripheral blood in vitro.

Methods: DCs in peripheral blood were cultured for five days with medium which had GM-CSF and IL-4. The compound traditional Chinese medicine were added into the medium and the cells were collected on the 5th day.

View Article and Find Full Text PDF

Aim: To explore the effects of pcDNA3.1-IL-15 transfected on co-stimulatory molecule expression and immune function on murine bone marrow-derived dendritic cells (DCs).

Methods: Recombinant plasmid pcDNA3.

View Article and Find Full Text PDF