Synopsis of recent research by authors named "Yan-Ji He"
- Yan-Ji He's recent research focuses on the mechanisms of cardiac regeneration and repair, particularly through the role of chemokine CCL2 and its activation of the JNK/STAT3 signaling axis during myocardial infarction recovery.
- His work also investigates the impact of heavy metal ions, specifically cadmium, on genomic instability in male spermatocytes, revealing that it impairs DNA repair mechanisms while influencing protein phosphorylation pathways.
- Furthermore, He explores novel therapeutic approaches for heart failure, demonstrating that the porcupine inhibitor CGX1321 can alleviate heart failure with preserved ejection fraction (HFpEF) by blocking the WNT signaling pathway, highlighting the importance of targeting this pathway in treating cardiac conditions.