Safflower (Carthamus tinctorius L.) has received a significant amount of attention as a medicinal plant in China. Flavonoids are the dominant active medical compounds.
Flavonoids are important secondary metabolites in safflower, contributing to plant growth and human health, yet research on the biosynthetic genes, particularly for quinochalcones, is limited.
A gene called CtF3H was isolated and confirmed to relate to flavonoid production, showing high similarity to F3H genes in other plants and was found in both the nucleus and cytosol of cells.
Transcriptome analysis revealed differing expression patterns of CtF3H between two safflower types under methyl jasmonate treatment, with an increase in specific flavonoids in quinochalcone-type safflower and different accumulation patterns in flavonol-type safflower.