Publications by authors named "Yan-Hong Xing"

Purpose: Women remain underrepresented in medical physics in the United States, and determinants of persisting disparities remain unclear. Here, we performed a detailed investigation of American Association of Physicists in Medicine (AAPM) membership trajectories to evaluate trends in Full membership with respect to gender, age, and highest degree.

Methods And Materials: Membership data, including gender, date of birth, highest degree, membership type, and years of active membership for 1993 to 2023 were obtained from AAPM.

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Objective: To explore the effectiveness of formative evaluation in the mentoring of student nursing interns in an emergency department.

Methods: A total of 144 intern nursing students in the emergency department of a tertiary care hospital in Fuzhou were selected as the study subjects from July 2020 to February 2021. Adopting quasi-experimental studies methods, the students were divided into the experiment group ( = 74) and the control group ( = 70), based on their practicing rotation times.

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Article Synopsis
  • Postoperative cognitive dysfunction (POCD) is a serious issue that can occur after anesthesia and surgery, particularly in younger patients, and this study explores the impact of silencing a specific gene (BACE1) on this condition.
  • Researchers used rat models to investigate how BACE1 gene silencing affects cognitive abilities and brain health after exposure to isoflurane anesthesia, focusing on signaling pathways that influence cell survival and inflammation.
  • Results showed that silencing BACE1 improved memory and reduced damaging effects on the brain, suggesting it could help protect against cognitive impairment resulting from anesthesia.
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Background And Purpose: Neuropeptide FF (NPFF) behaves as an endogenous opioid-modulating peptide. In the present study, the opioid and NPFF pharmacophore-containing chimeric peptide BN-9 was synthesized and pharmacologically characterized.

Experimental Approach: Agonist activities of BN-9 at opioid and NPFF receptors were characterized in in vitro cAMP assays.

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The Bennett and Xie (1988) model of chronic constriction injury (CCI) investigated the effects of tetramethylpyrazine (TMP) on neuropathic pain-associated behaviors and neuronal apoptosis in the spinal dorsal horn. Fifty-four male rats were randomly divided into sham (group S), CCI (group C) and TMP groups (group T). Each group was divided into subgroups (n = 6 in each group) according the time of sacrifice: 3 d, 7 d and 14 d.

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Objective: To explore the effects of α(2) adrenergic receptor (α(2)AR) agonists clonidine and dexmedetomidine on the injury model of peripheral nerve chronic constriction in rats.

Methods: A total of 72 male SD rats weighing 180 - 250 g were randomly divided into 4 groups (n = 18 each). In sham operation group (S), the right sciatic nerves were exposed but not ligated.

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Objective: To explore the effect of FPS on low-density lipoprotein acceptor (LDL-R) mRNA in the liver tissues of hyperlipidemic rats.

Methods: Sixty healthy male SD rats were randomly divided into six groups: normal control, model control, Gynostemma pentaphyllum, FPS low dosage, FPS moderate dosage, and FPS high dosage group. Excepting the rats in the normal control group, the ones in other groups were all made rats' hyperlipidemic model by irrigating hyperlipidemic emulsion into the stomach and observed the expression of LDL-R mRNA in the liver tissues of rats of each group.

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