Publications by authors named "Yan-Hong Tuo"
Background: Lupus nephritis is one of the most serious complications of systemic lupus erythematosus (SLE). Ten percent to 20% of patients with SLE progress to end-stage renal disease and would require renal replacement therapy or renal transplantation. In this analysis, we aimed to systematically compare mortality and the causes of mortality in patients with complicated SLE who were treated on hemodialysis (HD) versus peritoneal dialysis (PD).
View Article and Find Full Text PDFWhether Mineralocorticoid receptor antagonists (MRA) reduce mortality and cardiovascular effects of dialysis patients remains unclear. A meta-analysis was designed to investigate whether MRA reduce mortality and cardiovascular effects of dialysis patients, with a registration in INPLASY (INPLASY2020120143). The meta-analysis revealed that MRA significantly reduced all-cause mortality (ACM) and cardiovascular mortality (CVM).
View Article and Find Full Text PDFBackground: Blood pressure (BP) variability is highly correlated with cardiovascular and kidney outcomes in patients with chronic kidney disease (CKD). However, appropriate BP targets in patients with CKD remain uncertain.
Methods: We searched PubMed, Embase, and the Cochrane Library for randomized controlled trials (RCTs) of CKD patients who underwent intensive BP management.
Background: The application of laparoscopic catheterization technology in peritoneal dialysis (PD) patients has recently increased. However, the advantages and disadvantages of laparoscopic versus conventional open PD catheter placement are still controversial. The aim of this meta-analysis is to assess the complications of catheterization in PD patients and to provide a reference for choosing a PD-catheter placement technique in the clinic.
View Article and Find Full Text PDFArticle Synopsis
- Hepatocellular carcinoma (HCC) is the most common type of liver cancer, and scientists are studying how certain molecules, called long noncoding RNAs, can affect cancer growth.
- Researchers found that a specific long noncoding RNA called LINC00346 is increased in HCC cells and that making it more active leads to less cancer cell growth and encourages cancer cell death.
- The study discovered that LINC00346 also affects the JAK-STAT3 pathway, which is important in cancer, suggesting it could be useful as an indicator for liver cancer in the future.