Publications by authors named "Yan-Hong Tian"

Article Synopsis
  • The study evaluated the effectiveness of a new chemotherapy regimen with levofloxacin in patients with pulmonary tuberculosis and Type-2 diabetes.
  • The experimental group showed a higher treatment success rate of 90% compared to 67.5% in the control group, with significant improvements in immune indicators.
  • Although the incidence of adverse reactions was similar between both groups, the experimental group had a significantly higher rate of negative sputum conversion over time.
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Objective: To observe the clinical efficacy of thymosin alpha 1 (Tα1) combined with multi-modality chemotherapy in patients with pulmonary tuberculosis (PTB) complicated with diabetes and discuss the effects of such combination therapy on lymphocyte subsets and sputum levels of cytokines.

Methods: A total of 120 patients with PTB complicated with diabetes admitted to the Affiliated Hospital of North China University of Science and Technology from January 2017 to January 2018 were included in this study and randomly divided into an experimental group (Tα1 group, n=60) and a control group (n=60). Clinical efficacy and adverse drug reactions were observed and compared between the two groups.

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In the title compound, C(14)H(15)N(3)O(2), the C=C(H)-C=O grouping and the imidazolidine ring are coplanar as a result of an intra-molecular N-H⋯O hydrogen bond and extended electronic conjugation. Inter-molecular N-H⋯O and O-H⋯N hydrogen bonds help to establish the packing.

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