Integration of machine learning prediction and heuristic optimization for mask delivery in COVID-19.

The novel coronavirus pneumonia (COVID-19) has created huge demands for medical masks that need to be delivered to a lot of demand points to protect citizens. The efficiency of delivery is critical to the prevention and control of the epidemic. However, the huge demands for masks and massive number of demand points scattered make the problem highly complex.

[The protective effects on the function and structure of retinae in diabetic rats by intravitreal injection of cyclosporin A].

Objective: To investigate the electrophysiological and morphological changes of retinae after intravitreal injection of cyclosporin A (CsA) in experimental diabetic rats.

Methods: Experimental study. SD diabetic mellitus (DM) rat models were induced with intraperitoneal injection of streptozotocin.

[Long-term survival analysis in 89 adult patients with acute myeloid leukemia of fusion gene aml1/eto positive].

This study was aimed to investigate various factors influencing long-term survival in adult AML patients with fusion gene aml1/eto positive. A single institutional retrospective study with long-term follow-up was performed to better define the prognostic factors for AML patients with aml1/eto positive. Newly diagnosed 89 adult AML patients with aml1/eto positive were followed up for 1 to 42 months (median 24 months) from January 2004 to July 2008.

[Seasonal variation and temperature sensitivity of soil respiration under different plant communities along an elevation gradient in Wuyi Mountains of China].

Taking the National Nature Reserve in Wuyi Mountains as experimental site, the seasonal variation and temperature sensitivity of soil respiration under four plant communities along an elevation gradient were studied, with their relations to the main environmental factors analyzed. The results showed that the soil respiration under the four plant communities had the same seasonal pattern, with the maximum (3.10-6.

[Variations of soil labile organic carbon along an altitude gradient in Wuyi Mountain].

By using sequential fumigation-incubation method, this paper determined the soil labile organic carbon (LOC) content under evergreen broadleaf forest, coniferous forest, sub-alpine dwarf forest, and alpine meadow along an altitude gradient in Wuyi Mountain National Nature Reserve in Fujian Province of China, with its relations to soil microbial biomass carbon (MBC), total organic carbon (TOC), total nitrogen (TN), and fine root biomass (FRB) analyzed. The results showed that soil LOC occupied 3.40%-7.

[Genotyping of HLA-DRB by oligonucleotide arrays in Han populations in southern China].

Objective: To develop an oligoneucleotide array for HLA-DRB typing and evaluate its function in comparison with that of PCR-SSP typing.

Methods: According to the specific allele sequences of HLA-DRB loci in Han populations in Southern China, 44 synthesized typing probes were immobilized on a glass supports. A pair of group-specific primers was designed according to the sequence of HLA-DRB exon2, then the primers and Cy5-dCTP were used in PCR, thus the PCR products were labeled with Cy5.