Hydrothermal cracking involves the conversion of organic waste into efficient fertilizer through hydrolysis at temperatures ranging from 180 to 220 °C and pressures of 1.5 to 2.45 MPa, which offers significant advantages in shortening the production cycle, enhancing efficiency, and decomposing antibiotics.
View Article and Find Full Text PDFChemotherapy combined with surgery is an important clinical treatment for glioma, but endogenous or acquired temozolomide (TMZ) resistance can lead to poor prognosis. microRNA (miR)-9-5p acts in biological function of glioma, but the drug resistance of miR-9-5p in glioma is under exploration. The study intended to test the molecular mechanism of miR-9-5p in glioma cells.
View Article and Find Full Text PDFA novel metal-organic framework (MOF) has been produced via Cu(NO)·6HO reaction with 3-(1-tetrazol-5-yl)pyridine (HL) in water, and its chemical formula is {[(Cu(L)(HO)](HO)) } (). Due to its high density of coordinately unsaturated sites along with large one-dimensional (1D) hexagonal channels, the activated complex () was explored as the solvent-free heterogeneous catalyst for cyanosilylation under mind conditions. The inhibitory function of compound against the survival rate of OS-732 osteosarcoma cells was evaluated via Cell Counting Kit-8 (CCK-8) detection kit.
View Article and Find Full Text PDFCancer cells are considered to have high morphological heterogeneity in human melanoma tissue. Here, we report that epithelial cancer cells are dominant in different development stages of human melanoma tissues. The cellular and molecular mechanisms that maintain melanoma cells in the epithelial state are further investigated in the A2058 cell line.
View Article and Find Full Text PDFThe interactions of nine typical municipal solid waste (MSW) fractions during pyrolysis were investigated using the thermogravimetric analyzer (TGA). To compare the mixture results with the calculation results of superposition of single fractions quantitatively, TG overlap ratio was introduced. There were strong interactions between orange peel and rice (overlap ratio 0.
View Article and Find Full Text PDFEur J Drug Metab Pharmacokinet
June 2015
GNF-351 is a candidate drug used to treat some diseases through antagonizing aryl hydrocarbon receptor. In the present study, molecular docking method was employed to understand the interaction between ketoconazole and GNF-351. The structure of cytochrome P450 (CYP) 3A4 was obtained from protein data bank, and 2-dimensional structure of GNF-351 with standard bond lengths and angles was drawn using chemdraw software.
View Article and Find Full Text PDFAn incineration experiment using simulated municipal solid waste (MSW) in the tubular furnace was performed to study the effects of SiO2, Al2o3 and CaO on the partitioning of Cd and Pb under different operating conditions which included adsorbents percentage, furnace temperature and residence time. The results indicated that the increasing of SiO2, AL2O3, CaO concentration were favorable for Cd to partition in the bottom ash. And for Pb, SiO2 and Al2O3 had the same effects.
View Article and Find Full Text PDFRegulations of intracellular protein kinase C (PKC) on carbachol (CCh)-induced intracellular calcium ([Ca(2+)]i) responses were investigated in different stages of melanoma cells. We found that CCh (1 mM) significantly increased [Ca(2+)]i with 6-, 4-, 4-, and 25-folds intensities in WM793B, 451Lu, SK-MEL-5, and A2058 melanoma cells, respectively. Pretreatment of phorbol 12, 13-dibutyrate (PDBu, 2 microM), an activator of intracellular PKC, significantly suppressed CCh-induced peak reactions in WM793B, SK-MEL-5, and A2058 cells.
View Article and Find Full Text PDFThe effect of sulfur compounds (including sulfur, sulfide, sulfite and sulfate), initial concentration of heavy metal and operating conditions on Pb emission in MSW incineration were investigated using a simulated tubular furnace with the simulated MSW. Operating conditions of the experiment included combustion chamber temperature and MSW residence time. The concentration of Pb was measured by ICP-AES after the digesting of samples including bottom ash, fly ash and flue gas according to related USEPA methods.
View Article and Find Full Text PDFThe effects of chlorides (including inorganic chloride NaCl and organic chloride PVC) on Cd emission in MSW (municipal solid waste) incineration was investigated using a simulated tubular furnace and the simulated MSW spiked with heavy metals. The concentrations of heavy metals were measured by ICP-AES after the digesting of samples including bottom ash, fly ash and flue gas according to related USEPA Methods. Heavy metal species in bottom ash and fly ash were identified by X-ray diffraction technique and the spectra of elements distributed and micrographs of bottom ash and fly ash were detected by energy dispersive X-ray system and scanning electron microscope, respectively.
View Article and Find Full Text PDFSheng Wu Gong Cheng Xue Bao
September 2006
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
January 2003
Aim: To detect the production of IgG and IgM by cultured umbilical blood B cell stimulated by UV and heat-inactivated Epstein-Barr virus (EBV).
Methods: Mononuclear cells were isolated routinely from umbilical blood, then monocytes, NK cells and cytotoxic T cells were eliminated by L-leucine methy ester method; remained T cells were eliminated by AET-SRBC rosette method. The purified B cells were treated with UV or heat-inactivated EBV respectively and cultured in complete IMDM.