Publications by authors named "Yan-Fang Huang"

Article Synopsis
  • * The study introduces a new one-dimensional Cu-MOF called DDA-Cu, which features a unique structure that enhances lithium-ion storage and structural stability, making it a robust and high-capacity cathode.
  • * DDA-Cu demonstrates impressive performance with a capacity of 353 mAh g-1 and retains 78% of its capacity after 1000 cycles, even showing strong functionality in a low electrolyte environment, outperforming other state-of-the-art MOF electrodes.
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  • * A new porous conductive metal-organic framework (MOF) was developed, which combines nitrogen-rich molecules and CuO units to create a stable and efficient anode for potassium storage.
  • * This MOF displays impressive performance at 60 °C, achieving an initial capacity of 455 mAh/g and maintaining 96.7% capacity retention over 1600 cycles, surpassing other high-temperature KIB anodes.
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Objective: This study aimed to evaluate the effectiveness of smart health-based rehabilitation on patients with poststroke dysphagia (PSD).

Methods: We recruited 60 PSD patients and randomly allocated them to the intervention ( = 30) and control ( = 30) groups. The former received the smart health-based rehabilitation for 12 weeks, whereas the latter received routine rehabilitation.

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  • PD-L1 is linked to tumor growth and immune evasion in diffuse large B cell lymphoma (DLBCL), but its upstream mechanisms are not fully understood.
  • In the study, researchers examined DLBCL cell lines and patient samples, discovering that MALAT1 interacts with miR-195, which negatively regulates PD-L1.
  • Knockdown of MALAT1 led to increased levels of miR-195, reduced PD-L1, and decreased cell proliferation and migration, enhancing cell death and immune response in DLBCL cells.
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  • The study assessed the effectiveness and side effects of a combination chemotherapy regimen (paclitaxel, 5-fluorouracil, leucovorin - TFL) in treating advanced gastric cancer (AGC) in 113 patients.
  • Out of the patients, 43.4% showed positive responses, with three complete responses and 46 partial responses, while others had stable or progressive disease.
  • The therapy was manageable in terms of side effects, with the most common severe toxicities being leukopenia and neutropenia, and it demonstrated promising median overall survival of 14.1 months.
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Histone H3 lysine 9 dimethylation (H3K9me2) hypermethylation is thought to be a major influential factor in cellular reprogramming, such as somatic cell nuclear transfer (SCNT) and induction of pluripotent stem cells (iPSCs). The diazepin-quinazolin-amine derivative (BIX-01294) specifically inhibits the activity of histone methyltransferase EHMT2 (euchromatic histone-lysine N-methyltransferase 2) and reduces H3K9me2 levels in cells. The imprinted gene small nuclear ribonucleoprotein N (Snrpn) is of particular interest because of its important biological functions.

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  • The study aimed to compare cardiovascular responses and angiotensin II levels in hypertensive patients during tracheal intubation using either an intubating laryngeal mask airway (ILMA) or a direct laryngoscope (DLS).
  • A total of 120 hypertensive patients were randomly assigned to two groups, and variations in arterial blood pressure and angiotensin II were measured before and after intubation.
  • Results showed that cardiovascular responses and angiotensin II levels were significantly lower in the ILMA group compared to the DLS group, suggesting that ILMA may lead to safer intubation with less cardiovascular risk.
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