Publications by authors named "Yan-Dong Wen"
Article Synopsis
- Recent research indicates that many patients with functional dyspepsia (FD) don't respond well to standard treatments like prokinetic agents and acid suppressors, leading to the exploration of traditional Chinese herbs, specifically Biling Weitong Granules (BLWTG), for relief from epigastric pain syndrome (EPS).
- A rigorous clinical trial evaluated the efficacy and safety of BLWTG over 6 weeks, comparing its effects to a placebo on patients suffering from EPS related to FD, monitoring pain severity, frequency, and any adverse effects.
- Results showed significant improvement in pain symptoms and resolution rates for those treated with BLWTG compared to the placebo, with a notable percentage of patients experiencing relief and better overall clinical scores over
Chinese medicine (CM) decoction placebo is one of the key factors restricting the placebo-controlled clinical trial of CM. In this article, based on the analysis of the diffificulties in preparing CM placebo, the production requirements for placebo were put forward. Moreover, in accordance with clinical practices, a production method and evaluation process of CM decoction placebo was proposed, to provide a reference for clinical research.
View Article and Find Full Text PDFA series of 3-alkoxy(phenyl)thiophosphorylamido-2-(per-O-acetylglycosyl-1'-imino)thiazolidine-4-one derivatives were prepared by the reaction of 1-alkoxy(phenyl)thiophosphoryl-4-(per-O-acetylglycosyl) thiosemicarbazides with ethyl bromoacetate. (1)H/(13)C HMBC measurements corroborated by X-ray crystallographic results revealed the exclusive regioselectivity of these ring closures toward the N-2 position of the thiosemicarbazide moiety. The bioactivity data of 3a-k suggest that the thiazolidine-4-one ring is critical for the herbicidal and fungicidal activities.
View Article and Find Full Text PDF