Screening for Obstructive Sleep Apnea in the Assessment of Coronary Risk.

There is increasing awareness that health screening may prevent some acute coronary events. Yet, obstructive sleep apnea (OSA) is seldom screened for and its relation with coronary risk markers is not well established. Consecutive adults (n = 696) enrolled in a cardiovascular health screening program were approached to determine the feasibility of incorporating OSA screening.

Validation of NoSAS score for screening of sleep-disordered breathing in a multiethnic Asian population.

Purpose: The NoSAS score was developed to identify subjects at high risk of sleep-disordered breathing (SDB). We aimed to validate the NoSAS score in a multiethnic Asian cohort and compare its performance to the STOP-Bang and Berlin questionnaires.

Methods: A sample of 242 subjects selected from a population-based cohort in Singapore completed home-based sleep testing with an Embletta device (type 3 monitor).

Predicting obstructive sleep apnea using the STOP-Bang questionnaire in the general population.

Objective: The STOP-Bang questionnaire was developed as a quick and simple screening tool for obstructive sleep apnea (OSA) in preoperative clinics. We aimed to evaluate the validity of the STOP-Bang questionnaire to predict moderate-to-severe and severe OSA in the general population.

Methods: A sample of 242 subjects selected from a population-based cohort in Singapore completed home-based sleep testing with a type 3 monitor.

Using the Berlin Questionnaire to Predict Obstructive Sleep Apnea in the General Population.

Study Objectives: The Berlin questionnaire is a self-administered questionnaire that was developed to identify subjects with obstructive sleep apnea (OSA) in primary care settings. This study evaluated the performance of the questionnaire to predict OSA in the general population.

Methods: A sample of 242 subjects in a population-based cohort completed a home-based sleep study with an Embletta device (type 3 monitor).

Prevalence of sleep-disordered breathing in a multiethnic Asian population in Singapore: A community-based study.

Background And Objective: Limited data exist on the prevalence variation in sleep-disordered breathing (SDB) across different Asian ethnicities. This population study aimed to estimate the prevalence of SDB in Singapore, a multiethnic nation, and to quantify the prevalence variation among Chinese, Malays and Indians.

Methods: The Singapore Health Study 2012 was a cross-sectional population study conducted on adults aged 21-79 years.

Antiviral activity of lanatoside C against dengue virus infection.

Dengue infection poses a serious threat globally due to its recent rapid spread and rise in incidence. Currently, there is no approved vaccine or effective antiviral drug for dengue virus infection. In response to the urgent need for the development of an effective antiviral for dengue virus, the US Drug Collection library was screened in this study to identify compounds with anti-dengue activities.