Publications by authors named "Yan Wei Sun"

In the new era, ecological restoration of territorial space is the important task of maintaining regional ecological security, improving regional ecological quality and providing high-quality ecological products. From the perspective of ecological security, accurately determination of key areas to be restored in the territorial space is the primary work, and it is also a key and difficult problem to scientifically carry out ecological restoration. Based on the mainstream ecological security pattern theory, taking Shanghai as the research area, we integrated morphological spatial pattern analysis method and InVEST model to identify ecological sources, extracted ecological corridors, ecological "pinch points" and obstacle points with circuit theory, comprehensively determined the key areas to be restored, and proposed targeted restoration strategies.

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This study explored the clinical effectiveness of antibiotic-loaded bone cement (ALBC) combined with vacuum-assisted closure (VAC) on the treatment of Wagner 3-4 diabetic foot ulcers (DFUs). This is a retrospective study, including 32 patients with Wagner 3-4 DFUs who had undergone treatment between August 2019 and June 2021. Patient age, sex, Hemoglobin A1c (HbA1c), body mass index (BMI), ankle brachial index (ABI), white blood cells (WBC), C-reactive protein (CRP) levels, comorbidities and wound closure methods were recorded.

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Article Synopsis
  • Sulforaphane (SFN) treatment for 48 hours significantly increased the number of acute myeloid leukemia cells in the G/M phase of the cell cycle, with more than half of KG1a cells and a large majority of KG1 cells showing this arrest.
  • * Flow cytometry and molecular analysis indicated that SFN activates the P53 signaling pathway, leading to increased expression of P53 and P21 while decreasing CDC2, a key protein that regulates cell cycle progression.
  • * The overall findings suggest that SFN could be a potential therapeutic agent by promoting G/M phase arrest in leukemia cells, thereby inhibiting their growth through the modulation of cell cycle-related gene expression.
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Considering a background of global warming, the effect of urban heat island (UHI) has become a serious ecological and environmental problem that is commonly faced by modern cities worldwide, posing challenges to the physical and mental health of residents in urban areas, air quality, and the healthy growth of surface vegetation. Using time series MODIS land surface temperature data products from 2001 to 2018, we evaluated the urban heat island intensity (UHII) and its spatiotemporal patterns in 1232 major urban human settlement patches (area>10 km) across China based on the consistency method. A random forest regression model (RF) was also used to reveal the driving mechanism of urban heat island intensity in China due to human activities, urban morphology, vegetation, topography, and meteorological factors.

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Porcine circovirus (PCV) is one of the smallest known DNA viruses in mammals. At present, PCVs are divided into three species, PCV1, PCV2, and PCV3. PCV1 and PCV2 were found in the 1970s and the 1990s, respectively, whereas PCV3 was discovered recently in 2016.

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Introduction: Previous results have indicated that CXCR4 is an oncogene in several types of human tumors including renal cell carcinoma (RCC). However, the correlation between CXCR4 expression and clinicopathological characteristics of RCC remains unclear.

Materials And Methods: We conducted a meta-analysis to quantitatively evaluate the association of CXCR4 expression with the incidence of RCC and clinicopathological characteristics.

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The exact roles of various granule-associated proteins (GAPs) of polyhydroxybutyrate (PHB) are poorly investigated, particularly for bacteria associated with plants. In this study, four structural GAPs, named phasins PhaP1 to PhaP4, were identified and demonstrated as true phasins colocalized with PHB granules in NGR234, a facultative microsymbiont of and many other legumes. The conserved PhaP2 dominated in regulation of granule size under both free-living and symbiotic conditions.

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Previous studies have identified that perilipin-1 (PLIN1) is a highly specific marker for liposarcoma. However, its functions have yet to be fully elucidated. The aim of the present study was to investigate the potential role of PLIN1 in the proliferation, migration and apoptosis of liposarcoma cells.

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Phosphate homeostasis is tightly modulated in all organisms, including bacteria, which harbor both high- and low-affinity transporters acting under conditions of fluctuating phosphate levels. It was thought that nitrogen-fixing rhizobia, named bacteroids, inhabiting root nodules of legumes are not phosphate limited. Here, we show that the high-affinity phosphate transporter PstSCAB, rather than the low-affinity phosphate transporter Pit, is essential for effective nitrogen fixation of Sinorhizobium fredii in soybean nodules.

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Although histone H3K9 methylation has been intensively studied in animals and a model plant Arabidopsis thaliana, little is known about the evolution of the histone methyltransferase and its roles in plant biotic stress response. Here we identified a Nicotiana benthamiana homolog of H3K9 histone methyltransferase KRYPTONITE (NbKYP) and demonstrated its fundamental roles on methylation of plant and virus, beside of leading to the suppression of endogenous gene expression and virus replication. NbKYP and another gene encoding DNA methyltransferase CHROMOMETHYLTRANSFERASE 3 (NbCMT3-1) were further identified as the key components of maintenance of transcriptional gene silencing, a DNA methylation involved anti-virus machinery.

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Most of the world's natural fiber comes from cotton (Gossypium spp.), which is an important crop worldwide. Characterizing genes that regulate cotton yield and fiber quality is expected to benefit the sustainable production of natural fiber.

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Background: Jatropha curcas is recognized as a new energy crop due to the presence of the high amount of oil in its seeds that can be converted into biodiesel. The quality and performance of the biodiesel depends on the chemical composition of the fatty acids present in the oil. The fatty acids profile of the oil has a direct impact on ignition quality, heat of combustion and oxidative stability.

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By using mcirolysimeter, a laboratory simulation experiment was conducted to study the effects of the grain size and thickness of dust deposits on the soil water evaporation and salt movement in the hinterland of the Taklimakan Desert. Under the same initial soil water content and deposition thickness condition, finer-textured (<0.063 mm) deposits promoted soil water evaporation, deeper soil desiccation, and surface soil salt accumulation, while coarse-textured (0.

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