Background: Azolla is a small floating fern living in symbiosis with nitrogen-fixing cyanobacteria and provides a variety of important ecosystem benefits. Previous studies have presented that Azolla harbors diverse bacteria that may play a key role in host fitness and productivity. However, the characteristics of endophytic bacteria inhabiting the phyllosphere of different species of Azolla have not yet been fully understood.
View Article and Find Full Text PDFFour new lignanamides, hancamides A - D (1-4), together with four known analogs (5-8), were isolated from the stems of Piper hancei Maxim. Their structures were determined based on 1D and 2D NMR, IR, UV, and HR-ESIMS spectroscopic analysis as well as by comparison with the reported data. All the isolates exhibited potential inhibitory effects on NO production in LPS-induced BV-2 microglial cells, with IC values of 4.
View Article and Find Full Text PDFReactive oxygen species (ROS) production by activation of microglia is considered to be a major cause of neuronal dysfunction, which can lead to damage and death through direct oxidative damage to neuronal macromolecules or derangement of neuronal redox signaling circuits. BAP31, an integral ER membrane protein, has been defined as a regulatory molecule in the CNS. Our latest studies have found that BAP31 deficiency leads to activation of microglia.
View Article and Find Full Text PDFSix new (-) and two known (, ) alkaloids that were chemically inseparable geometrical isomers (two isomers present in a 1:1 ratio for - and and a 1:3 ratio for , , and ) were identified from . Their structures and absolute configurations were determined by spectroscopic data analyses and comparison of their experimental and calculated ECD spectra. Moreover, using NOE correlations and DFT-based calculations, the NMR data of each geometrical isomer of - were assigned.
View Article and Find Full Text PDFA phytochemical investigation of the aqueous EtOH extract of tubers afforded 34 phenanthrene and 9,10-dihydrophenanthrene derivatives, including four new compounds, -. These compounds were identified using physicochemical analyses and various spectroscopic methods. Twelve of these compounds were resolved into their enantiomers, and the absolute configurations were determined by comparison of experimental and calculated ECD spectra.
View Article and Find Full Text PDFSeventeen compounds, including three new pairs of coumarinolignoid enantiomers, (7' S,8' S)-sapiumins A-C (1a-3a) and (7' R,8' R)-sapiumins A-C (1b-3b), six new taraxerane triterpenoids, sapiumic acids A-F (4-9), and five known taraxerane triterpenoids (10-14), were isolated from an ethanol extract prepared from the stems and leaves of Sapium discolor. The structures of 1-9 and their relative configurations were determined by spectroscopic data analysis, and the absolute configurations of the coumarinolignoids 1a/1b-3a/3b and triterpenoids 6-9 were assigned using experimental and calculated ECD data. Compounds 1a/1b-3a/3b are the first coumarinolignoids to be reported from the genus Sapium.
View Article and Find Full Text PDFObjective: To ascertain the feasibility of using shear wave velocity (SWV) in assessing the stiffness of carotid plaque by supersonic shear imaging (SSI) and explore preliminary clinical value for such evaluation.
Materials And Methods: Supersonic shear imaging was performed in 142 patients with ischemic stroke, including 76 males and 66 females with mean age of 66 years (range, 45-80 years). The maximum, minimum, and mean values of SWV were measured for 129 carotid plaques.
In the construction of coordination polymers, many factors can influence the formation of the final architectures, such as the nature of the metal centres, the organic ligands and the counter-anions. In the coordination polymer poly[aqua(μ-benzene-1,2-dicarboxylato-κO,O:O,O)[μ-2-(1H-imidazol-1-ylmethyl)-6-methyl-1H-benzimidazole-κN:N]cadmium(II)], [Cd(CHN)(CHO)(HO)] or [Cd(immb)(1,2-bdic)(HO)], each Cd ion is seven-coordinated by two N atoms from two symmetry-related 2-(1H-imidazol-1-ylmethyl)-6-methyl-1H-benzimidazole (immb) ligands, by four O atoms from two symmetry-related benzene-1,2-dicarboxylate (1,2-bdic) ligands and by one water molecule, leading to a CdNO distorted pentagonal bipyramidal coordination environment. The immb and 1,2-bdic ligands bridge Cd ions and form a two-dimensional network structure.
View Article and Find Full Text PDFTrop Anim Health Prod
February 2018
Schmallenberg virus (SBV) is an emerging and rampant arbovirus in Europe, and even Africa and West Asia. Investigating whether SBV existed in new regions or countries, it was very helpful for the early warning and control of SBV. In this study, we collected 317 serum samples (n = 242 for dairy cattle, n = 13 for yellow cattle, n = 21 for buffalo, and n = 41 for goats) from Guangdong province of southern China, which is located in a subtropical region and is an important distribution area for arboviral diseases.
View Article and Find Full Text PDFA novel 1,1'-bi-2-naphthol (BINOL) derivative fluorescence sensor L-1 for the recognition of thorium ion with a fluorescence quench response. This ligand showed high selectivity and sensitivity for thorium ion recognition. Coordination effects were investigated by DFT calculations, and the coordination modes and sites were confirmed.
View Article and Find Full Text PDFRehmannia is a medicinal plant in China. Autotoxicity has been reported to be one of the major problems hindering the consecutive monoculture of Rehmannia. However, potential autotoxins produced by the fibrous roots are less known.
View Article and Find Full Text PDFThe pathogenesis of tardive dyskinesia (TD) may involve neurodegeneration and associated dysfunction of brain-derived neurotrophic factor (BDNF) for the survival and maintenance of function in neurons. We therefore compared serum BDNF levels in schizophrenic patients with (n=129) and without TD (n=235), and normal controls (n=323). Assessments included the abnormal involuntary movement scale (AIMS) and the positive and negative syndrome scale (PANSS).
View Article and Find Full Text PDF