Publications by authors named "Yan Li Zhu"

Thermal batteries are a type of thermally activated reserve batteries, where the cathode material significantly influences the operating voltage and specific capacity of the battery. In this work, VS-VO has been synthesized through the hydrothermal method and used as the cathode material for thermal batteries. Firstly, the material with the VS crystallinity is obtained at 170 °C and the mass percentages of VS/VO are 63.

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As a promising solution for solid-state batteries with high energy density and safety, understanding the mechanism of fast ion conduction in polymer-ceramic composite solid-state electrolytes (CSEs) is still a challenging task. Herein, we understand the enhanced ion conduction in CSEs using a series of ionic spectra. Ionic insight is extended to ion conduction in CSEs, resolving the mechanism of fast ion migration.

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Thermal batteries are solid-state, thermally activated batteries with long storage times and high reliability. FeS is used as a cathode material commonly, but the high internal resistance and low voltage platform limit the improvement of battery performance. Herein, the 1T-phase vanadium disulfide (VS) is prepared via the scalable hydrothermal method and applied to thermal battery cathode materials for the first time.

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Owing to high-efficiency and scalable advantages of electrolysis in molten salts, electrochemical conversion of carbonaceous resources into graphitic products is a sustainable route for achieving high value-added carbon. To understand the complicated kinetics of converting amorphous carbon (e.g.

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Objective: This study aimed to assess the effects of multi-donor fecal microbiota transplantation (FMT) capsules combined with thalidomide on hormone-dependent ulcerative colitis (UC).

Methods: A total of 59 patients with steroid-dependent UC treated at the Gastroenterology Department of the First Affiliated Hospital of Xinxiang Medical University between January 2017 and January 2019 were enrolled in this study. Using a random number table, the patients were divided into two groups: a group treated with FMT capsules (the FMT group) and a group treated with FMT capsules and thalidomide (the FMT+S group).

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Article Synopsis
  • A new triple cascade amplification strategy was created for the ultra-sensitive detection of multiple cancer biomarkers using single particle inductively coupled plasma mass spectrometry (spICP-MS).
  • This strategy includes three main parts: a target recycling module using RNA bases for better efficiency, a hybridization chain reaction, and a signal amplification using DNA-templated metal nanoclusters to improve signal quality and reduce interference.
  • The spICP-MS platform showed high accuracy in detecting carcinoembryonic antigen (CEA) and alpha-fetoprotein (AFP) in human serum, outpacing traditional methods in sensitivity, operational simplicity, and range, suggesting it could be an effective tool for cancer diagnostics and research.
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Telomerase (TE) is recognized as a potential biomarker for early diagnosis, monitoring and treatment of cancer. At present, most of the methods for TE detection are only applicable to in vitro assays, and unsuitable for in vivo applications. Though a few intracellular probes have been reported to have good specificity for TE, they do not involve signal amplification, which hinders their applicability in scenarios requiring high sensitivity.

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Background: The International System for Reporting Serous Fluid Cytopathology (TIS) was recently proposed. We retrospectively applied TIS recommendations for reporting the cytological diagnosis of serous effusions and reported our experience.

Methods: All the serous effusions from January 2018 to September 2021 were retrieved from the database.

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  • A novel mass spectroscopic platform was developed for detecting microRNAs (miRNAs) by integrating ligation reactions, hybridization chain amplification, and multiple-metal-nanoparticle tagging.
  • The use of multiple-metal-nanoparticle tagging enhances both specificity and sensitivity, allowing the platform to effectively distinguish between target and non-target miRNAs, even with single-nucleotide differences.
  • Achieving limits of detection around 0.5 fM and quantitative results comparable to traditional methods, this platform shows promise for applications in clinical diagnosis and biomedical research.
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A facile MALDI-TOF mass spectrometric platform for quantitative analysis of protein biomarkers was developed based on magnetic ZnFeO nanoparticles and mass tagging signal amplification. In this platform, magnetic ZnFeO nanoparticles functionalized with an aptamer of the biomarker of interest was used to magnetically separate silica nanoparticles modified with another aptamer of the target biomarker and a barcoding peptide from solution phase in the presence of the biomarker of interest. After the silica nanoparticles were dissolved by KHF, the released barcoding peptide was detected by MALDI-TOF mass spectrometry with magnetic ZnFeO nanoparticles used as assisting matrix of laser desorption ionization.

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Density functional theory was employed to investigate the (111), (200), (210), (211) and (220) surfaces of CoS. The surface energies were calculated with a sulfur environment using first-principle-based thermodynamics. It is founded that surfaces with metal atoms at their outermost layer have higher energy.

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The objective of this article is to study the effect of inhibiting phosphatase and tensin homolog deleted chromatosome 10 gene on phosphoinositide 3-kinase/protein kinase B ()/Forkhead homeobox O3a signaling pathway in human nasopharyngeal carcinoma HK-1 cells. Nasopharyngeal carcinoma HK-1 cell lines were divided into gene interference group (siPTEN), nonspecific small interfering RNA group (siNC), empty vector group (Vector), and no transfection control group (Normal). The mRNA and protein expression levels of , , and were detected by real-time fluorescence quantitative polymerase chain reaction and Western blot.

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Intrathyroidal thymic carcinoma is a malignant epithelial tumor of the thyroid gland with thymic epithelial differentiation; it is the malignant counterpart of ectopic thymoma of the thyroid gland and histologically resembles thymic carcinoma. Given its favorable prognostic course, preoperative cytological diagnosis is important to distinguish this neoplasm from other more aggressive thyroid neoplasms that can have similar or overlapping cytomorphological features. However, there is little information about the cytology of this disease available in the literature, even in the latest fourth edition of World Health Organization classification of tumors of endocrine organs.

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A facile mass spectrometric kinetic method for quantitative analysis of chiral compounds was developed by integrating mass spectrometry based on chemical derivatization and the spectral shape deformation quantitative theory. Chemical derivatization was employed to introduce diastereomeric environments to the chiral compounds of interest, resulting in different abundance distribution patterns of fragment ions of the derivatization products of enantiomers in mass spectrometry. The quantitative information of the chiral compounds of interest was extracted from complex mass spectral data by an advanced calibration model derived based on the spectral shape deformation quantitative theory.

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Article Synopsis
  • Insulin resistance (IR) is recognized as a key factor in the development of metabolic syndrome (MetS) and needs to be monitored, especially in overweight individuals, for prevention and early intervention.
  • Research indicates that human umbilical cord mesenchymal stem cells (HUC-MSCs) could be a promising treatment for IR, particularly in conditions like type 2 diabetes mellitus (T2DM).
  • The text discusses the mechanisms of HUC-MSCs, their clinical advantages and disadvantages, and their current applications in treating T2DM, while acknowledging that further research is needed.
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  • The study measured volatile organic compounds (VOCs) during the composting process in Beijing's municipal solid waste facility using advanced gas chromatography.
  • Key findings revealed that the highest VOC concentrations were in the sorting room and first fermentation workshop, with ethanol, limonene, and acetone being the main compounds found.
  • The results indicated the need to reduce VOC emissions in these areas to lower their ozone formation potential, and the maximum incremental reactivity (MIR) scale was recommended for more accurately calculating this potential.
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Purpose: Borrmann type IV gastric cancer is still detected at an advanced stage and survival rates for these patients remain poor. The purpose of this study was to provide valuable prognostic and surgical information on patients with Borrmann type IV gastric cancer.

Methods: We compared the clinicopathological features of Borrmann type IV gastric cancer with those of other types of gastric cancer.

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Unlabelled: On the basis of total temperature increase, normal dehydration, and maturity, the odor compositions of surface and internal piles in a well-run sewage sludge compost plant were analyzed using gas chromatography-mass spectrometry with a liquid nitrogen cooling system and a portable odor detector. Approximately 80 types of substances were detected, including 2 volatile inorganic compounds, 4 sulfur organic compounds, 16 benzenes, 27 alkanes, 15 alkenes, and 19 halogenated compounds. Most pollutants were mainly produced in the mesophilic and pre-thermophilic periods.

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The circulation of duck hepatitis A virus types 1 (DHAV-1) and 3 (DHAV-3) in Southeast Asia has resulted in a continuously changing epidemiological scenario. In this study, a duplex real-time PCR assay for simultaneous quantitative detection of DHAV-1 and DHAV-3 was established, and 200 liver samples from dead ducklings collected from 31 different flocks in Shandong province, China, were tested. Fifty-eight (29.

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In mid-August 2013, two H9N2 influenza viruses, named A/mink/Shandong/F6/2013 (Mk/SD/F6/13) and A/mink/Shandong/F10/2013 (Mk/SD/F10/13), were isolated from lung samples of 2 of 45 farmed mink exhibiting respiratory signs in mideastern Shandong province, China. The seroprevalence of antibodies to H9N2 in mink was 20% (53/265). Based on sequence analysis, the eight nucleotide sequences showed 99.

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Spinal muscular atrophy (SMA) is a common autosomal recessive neuromuscular disorder caused by mutations of the survival of motor neuron 1 (SMN1) gene. Approximately 90-95% of SMA patients have a homozygous deletion of SMN1, and 5-10% of patients are believed to have subtle mutations. The molecular diagnosis of SMN1 subtle mutations is hampered by a highly homologous SMN2 gene.

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Article Synopsis
  • - The H5N2 influenza virus, isolated from a symptomatic dog in China in 2009, has been confirmed to transmit between dogs but its transmission to other species was unclear.
  • - Contact exposure experiments were conducted with susceptible cats and chickens housed near infected dogs, revealing that one cat showed clear infection and others had seroconversion, while eight chickens displayed signs of illness and two died.
  • - The results suggest that close contact with H5N2-infected dogs can lead to the virus spreading to both cats and chickens, indicating possible interspecies transmission.
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Background: The molecular work-up of thyroid nodules from fine needle aspiration samples has given clinicians a new level of diagnostic information. The aim of the present study was to evaluate the utility of molecular analysis in thyroid fine needle aspiration samples from a Chinese population.

Methods: Specimens were collected from thyroid nodules by fine needle aspiration.

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To reveal the genetic variation of the viral protein 1 (VP1) gene of the duck hepatitis A virus type 3 (DHAV-3), the VP1 gene of 13 virulent DHAV-3 strains isolated from Shandong province of China in 2012 were amplified by RT-PCR, sequenced and analyzed. The results showed that all the VP1 genes of the 13 isolates contained 720 nucleotides encoding 240 amino acids, and shared with nucleotide identities of 94. 6%-99.

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Article Synopsis
  • Duck hepatitis A virus (DHAV) causes a severe and lethal disease in young ducklings, with two types identified in China: DHAV-1 and DHAV-3.
  • A duplex RT-PCR assay was developed to effectively identify mixed infections of DHAV-1 and DHAV-3, demonstrating high specificity, sensitivity, and a detection limit of 10pg RNA from duck liver samples.
  • The study found that out of 60 liver samples from various provinces, 57.7% of flocks showed mixed infections, while 34.6% had single infections, highlighting the assay's potential for rapid and cost-effective diagnosis.
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