Improved Surface Quality and Microstructure Regulation in High Power Fiber Laser Cutting of Stainless Steel Grid Plates.

In order to disintegrate nuclear fuel rods in the grid connection structure, a 10 kW fiber laser was used to cut a stainless steel simulation component with four layers of 3 mm thick plates and 12 mm gaps. The slit width is regarded as an important indicator to evaluate the cutting quality of the four-layer stainless steel plate. The results showed that good laser cutting quality can be successfully achieved under the proper process parameters.

Determination of Geographical Origin of Southern Shaanxi Congou Black Teas Using Sensory Analysis Combined with Gas Chromatography-Ion Mobility Spectrometry.

Southern Shaanxi is one of China's high-quality congou black tea production areas. However, the differences in geography, cultivation, and management techniques and production processes lead to uneven qualities of southern Shaanxi congou black tea in different production areas. This study used sensory analysis combined with gas chromatography-ion mobility spectrometry (GC-IMS) to determine southern Shaanxi congou black teas' geographical origin and volatile fingerprints to prevent economic losses caused by fraudulent labeling.

Suboptimal distributed cooperative control for linear multi-agent system via Riccati design.

In this paper, we propose a suboptimal distributed cooperative control scheme for the continuous-time linear multi-agent system (MAS) with a specified global quadratic cost functional over both undirected and directed graph scenarios. For undirected graphs, we first derive the cost functional for a given strictly linear feedback distributed protocol. It is shown that the cost functional is upper bounded by a quadratic form of the MAS's initial state, and the minimum upper bound can be derived by solving a parametric algebraic Riccati equation (PARE) depends solely on the algebraic connectivity of the graph and is independent of the largest eigenvalue compared with the existing work.

Erythrocyte-Based Biomimetic MOFs as a Triple Epigenetic Regulator for Enhancing Anti-Leukemia Immunity.

While therapeutic strategies targeting epigenetic dysregulation hold promise for leukemia, epigenetic drugs face several limitations, including low utilization rates, the emergence of resistance, and off-target effects. The hypoxic microenvironment in leukemia further impairs drug sensitivity. Here, we synthesized an MOF-based erythrocyte biomimetic nanoplatform to enhance immune responses against leukemia by targeting three epigenetic modifications.

Glycoengineered extracellular vesicles released from antibacterial hydrogel facilitate diabetic wound healing by promoting angiogenesis.

Diabetic wounds have become a global healthcare burden owing to impaired angiogenesis and persistent infections. Extracellular vesicles (EVs) can improve diabetic wounds, though their targeting ability is limited. In this study, we investigated the performance of a novel hydrogel dressing comprised of gelatin methacryloyl, glycoengineered EVs, and polylysine in treating infected diabetic wounds.

Gender-specific relationships between hyperuricemia and idiopathic deep venous thrombosis in the Chinese population: a case‒control study.

Background: Many studies have indicated that hyperuricemia is positively correlated with secondary deep venous thrombosis (DVT); however, the risk factors for idiopathic DVT based on gender differences, such as serum uric acid (SUA) and hyperuricemia, have not been fully examined.

Objectives: To investigate the association between hyperuricemia and the occurrence of idiopathic lower extremity DVT based on gender differences.

Methods: This was a retrospective analysis of 4299 patients who were hospitalized at the Affiliated Hospital of Qingdao University from January 2012 to October 2021 and who underwent ultrasound of the lower limbs.

Amino-functionalized vertically ordered mesoporous silica film on electrochemically polarized screen-printed carbon electrodes for the construction of gated electrochemical aptasensors and sensitive detection of carcinoembryonic antigens.

Disposable electrochemical biosensors with high sensitivity are very fit for point-of-care testing in clinical diagnosis. Herein, amino-functionalized, vertically ordered mesoporous silica films (NH-VMSF) attached to an electrochemically polarized screen-printed carbon electrode (p-SPCE) are prepared using a simple electrochemical method and then utilized to construct a gated electrochemical aptasensor for rapid and sensitive determination of carcinoembryonic antigen (CEA). After being treated with the electrochemical polarization procedure, p-SPCE has plentiful oxygen-containing groups and improved catalytic ability, which help promote the stability of NH-VMSF on SPCE without the use of an adhesive layer and simultaneously generate a highly electroactive sensing interface.

A novel optical strategy for ALP detection and development of matched smartphone app.

Alkaline phosphatase (ALP) is a reliable biomarker for various diseases, making the development of new detection methods highly significant. Herein, we report a simple and accurate dual-signal optical detection strategy for measuring ALP activity across the entire clinical range in adults. Based on this, we designed a smartphone app to eliminate the limitations of large instruments, enabling real-time field detection.

Aroma characterization of Sichuan and Cantonese sausages using electronic nose, gas chromatography-mass spectrometry, gas chromatography-olfactometry, odor activity values and metagenomic.

The interest of Chinese consumers in meat-free sausages has increased considerably due to their health benefits, but the aroma quality is far from reaching the traditional fermented meat sausages. This study evaluated the aroma characterization of Sichuan and Cantonese sausages using electronic nose (E-nose), gas chromatography-mass spectrometry (GC-MS), gas chromatography-olfactometry (GC-O), odor activity values (OAVs) and metagenomic. Ninety-eight volatile compounds were identified.

The efficacy of Lactobacillus and Bifidobacterium in patients with schizophrenia: a meta-analysis.

The modulation of gut microbiota through probiotics holds promise as a novel avenue for schizophrenia treatment. This study aims to analyze probiotic complementary therapy on individuals with schizophrenia systematically, to investigate probiotic efficacy, potential mechanisms, and implications for clinical practice. Adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we searched in Medline, Web of Science, Embase, ClinicalTrials.

Novel variants in DNAH9 are present in two infertile patients with severe asthenospermia.

Asthenospermia is a type of sperm that has malformed sperm with movement disorders that lead to male infertility. DNAH9 is a member of the dynein family and a central part of the outer dynein arm of cilia and flagella. DNAH9 gene defects are associated with primary ciliary dyskinesia and ultrastructural abnormalities in ciliary axial ultrastructure.

Improvement of multiscale decomposition for space-based gravitational wave signal processing technology.

During the process of detecting gravitational waves in space, addressing noise issues caused by terrestrial vibrations, natural environmental changes, and the factors intrinsic to the detectors, this paper proposes a multiscale variational mode adaptive denoising algorithm based on momentum gradient descent. This algorithm integrates momentum factors and multiscale concepts into the variational mode algorithm to resolve the issue of multiple local optima encountered during operation, reduce oscillations in regions with large or unstable gradient changes, and improve convergence speed. Additionally, the algorithm combines the least mean squares algorithm to automatically adjust weights, thereby mitigating the impact of noise, addressing the issue of noise from multiple and random sources, effectively suppressing noise in the gravitational wave signal, and enhancing the quality and reliability of the gravitational wave signal.

Inulin alleviates atherosclerosis through improving lipid metabolism, inflammation, and gut microbiota in ApoE-knockout mice: the short-chain is more efficacious.

Introduction: Atherosclerosis (AS) is considered the underlying cause of many diseases, particularly cardiovascular and cerebrovascular diseases. Inulin, a type of fructan, has shown potential in improving atherosclerosis, although there are conflicting findings. It is hypothesized that the polymerization degree of inulin may largely influence its therapeutic effectiveness.

The NEDD4/FLRT2 axis regulates NSCLC cell stemness.

Introduction: Lung cancer is the leading cause of cancer-related death worldwide. The treatment for lung cancer, particularly for non-small cell lung cancer (NSCLC), remains a clinical challenge. Cancer stem cells are vital for lung cancer development.

Cystitis glandularis: MR imaging characteristics in 27 patients.

Purpose: To explore the diagnostic characteristics of cystitis glandularis (CG) using magnetic resonance imaging (MRI).

Materials And Methods: A retrospective study was conducted on pathologically confirmed patients who underwent bladder MRI examination between January 2019 and November 2023. Image analysis was jointly conducted, with emphasis on lesion location, morphology, size, signal intensity, and pattern of enhancement, by two genitourinary radiologists with 22 and 15 years of experience, respectively.

Electrochemical Detection of HO Using BiO/BiOSe Nanocomposites.

The development of high-performance hydrogen peroxide (HO) sensors is critical for various applications, including environmental monitoring, industrial processes, and biomedical diagnostics. This study explores the development of efficient and selective HO sensors based on bismuth oxide/bismuth oxyselenide (BiO/BiOSe) nanocomposites. The BiO/BiOSe nanocomposites were synthesized using a simple solution-processing method at room temperature, resulting in a unique heterostructure with remarkable electrochemical characteristics for HO detection.

First Report of Paprika mild mottle virus Infecting pepper ( L.) in China.

Paprika mild mottle virus (PaMMV), a tobamovirus from the Virgaviridae family, has been reported to infect pepper ( L.) in the Netherlands (García-Luque et al., 1993), Japan (Hamada et al.

Enhancing laboratory biosafety management: a comprehensive strategy from theory to practice.

Objective: This study examines biosafety management practices in a psychiatric hospital's laboratory in China, focusing on how outdated information technology impacts the hospital's ability to respond to public health emergencies. The goal is to enhance the hospital's emergency response capabilities by updating risk assessments, biosafety manuals, and implementing a comprehensive quality management system alongside a specialized infection control system for significant respiratory diseases.

Methods: We utilized an integrated research approach, expanding the scope of risk assessments, updating the biosafety manual according to the latest international standards, and implementing a quality management system.