Dibohemamines I-O from Streptomyces sp. GZWMJZ-662, an endophytic actinomycete from the medicinal and edible plant Houttuynia cordata Thunb.

A chemical investigation of Streptomyces sp. GZWMJZ-662, an endophytic actinomycete isolated from Houttuynia cordata Thunb., has yielded eleven bohemamine dimers (1-11).

[Expression and Clinical Significance of Serum HDAC2 in Patients with Acute Myeloid Leukemia].

Objective: To investigate the expression of serum histone deacetylase 2 (HDAC2) in patients with acute myeloid leukemia (AML) and its clinical significance.

Methods: The 150 AML patients who received treatment in our hospital from April 2017 to April 2019 were included as AML group, and further divided into survival group (108 cases) and death group (42 cases) according to their survival status. In addition, 100 health individuals undergoing health examination in the same period were included as control group.

Disentangling the effects of obesity and high-fat diet on glucose homeostasis using a photoperiod induced obesity model implicates ectopic fat deposition as a key factor.

Objective: Obesity in laboratory rodents is generally induced by feeding them a high fat diet (HFD). This model does not permit separation of the impact of the HFD from the resultant obesity on metabolic defects such as impaired glucose homeostasis. In Brandt's voles we have previously shown that exposure to long photoperiod (LD: 16L: 8D) induces obesity even when they are fed a low fat diet.

Photoalignment of dye-doped cholesteric liquid crystals for electrically tunable patterns with fingerprint textures.

We present a convenient photoalignment approach to fabricate rewritable fingerprint textures with designed geometrical patterns based on methyl red doped cholesteric liquid crystals (MDCLCs). MDCLC systems with/without nanoparticles of polyhedral oligomeric silsesquioxanes (POSS) were employed to realize two types of sophisticated binary patterns, respectively. Based on the understanding of involved mechanisms related to boundary conditions and middle-layer theory, we demonstrated the precise manipulation of fingerprint patterns by varying the fingerprint grating vectors in different domains.

Photoperiod induced obesity in the Brandt's vole (Lasiopodomys brandtii): a model of 'healthy obesity'?

Brandt's voles have an annual cycle of body weight and adiposity. These changes can be induced in the laboratory by manipulation of photoperiod. In the present study, male captive-bred Brandt's voles aged 35 days were acclimated to a short day (SD) photoperiod (8L:16D) for 70 days.

Effects of reproduction on immuno-suppression and oxidative damage, and hence support or otherwise for their roles as mechanisms underpinning life history trade-offs, are tissue and assay dependent.

Life history parameters appear to be traded off against each other, but the physiological mechanisms involved remain unclear. One hypothesis is that potentially energetically costly processes such as immune function and protection from oxidative stress may be compromised during reproductive attempts because of selective resource allocation. Lower temperatures also impose energy costs, and hence allocation decisions might be more pronounced when animals are forced to reproduce in the cold.

Ionic Ni(II) complexes containing a triphenylphosphine ligand and an imidazolium cation: synthesis, structures and catalysis for aryl Grignard cross-coupling of aryl halides.

Novel ionic Ni(II) complexes of general formula [R2im][Ni(PPh3)Cl3] (R2im = 1,3-bis(2,6-diisopropylphenyl)imidazolium cation, IPrim, 1a; R2im = 1,3-diisopropylimidazolium cation, (i)Prim, 2a) were easily prepared in high yields by the direct reaction of Ni(PPh3)2Cl2 with 1 equiv. of N,N'-dihydrocarbylimidazolium salt, [R2im]Cl. Their bromide analogs [R2im][Ni(PPh3)Br3] (R2im = IPrim, 1b; R2im = (i)Prim, 2b) were synthesized by the same reaction in the presence of excess NaBr.

No evidence for a trade-off between reproductive investment and immunity in a rodent.

Life history theory assumes there are trade-offs between competing functions such as reproduction and immunity. Although well studied in birds, studies of the trade-offs between reproduction and immunity in small mammals are scarce. Here we examined whether reduced immunity is a consequence of reproductive effort in lactating Brandt's voles (Lasiopodomys brandtii).

Partial removal of brown adipose tissue enhances humoral immunity in warm-acclimated Mongolian gerbils (Meriones unguiculatus).

Temperate rodent species experience marked seasonal fluctuations in environmental temperatures. High thermoregulatory demands during winter usually weaken immune function. Brown adipose tissue (BAT) plays a crucial role in adaptive thermoregulatory process.

Controlled synthesis of nickel(II) dihalides bearing two different or identical N-heterocyclic carbene ligands and the influence of carbene ligands on their structures and catalysis.

Ni(II) dihalides bearing two different or identical NHC ligands have been prepared via a controlled indene elimination synthesis, and the former product provides a new route for the design of biscarbene Ni(II)-based catalysts. The indene elimination reaction of the indenynickel(II) complex (1-H-Ind)Ni(NHC)X (Ind = indenyl) with one equiv. of a distinct imidazolium salt at 100 °C afforded the first example of Ni(II) dihalides bearing two different NHC ligands, i.