Publications by authors named "Yamini Umashankar"
The Influence of Biofilms on Carbapenem Susceptibility and Patient Outcome in Device Associated Infections: Insights Into Phenotype vs Genome-Wide Analysis and Correlation.
Naveen Kumar Devanga Ragupathi Dhiviya Prabaa Muthuirulandi Sethuvel Hariharan Triplicane Dwarakanathan Dhivya Murugan Yamini Umashankar
Front Microbiol
December 2020
Article Synopsis
- Nosocomial infections, particularly those caused by carbapenem-resistant pathogens, are increasing globally and their ability to form biofilms complicates patient management.
- The study investigates the relationship between biofilm formation, patient outcomes, and carbapenem resistance in isolates from patients in critical care, revealing a negative impact on patient survival associated with stronger biofilm formers.
- Genetic analysis showed specific sequence types of bacteria are linked to biofilm formation and drug resistance, with a unique correlation suggesting that traditional susceptibility tests may not accurately reflect treatment effectiveness due to biofilm environments.