Publications by authors named "Yamini Murghai"
Article Synopsis
- Mitochondria-targeting agents, or mitocans, are becoming promising cancer treatments due to their effects on cancer cell metabolism and apoptosis, with ONC212 being a key compound studied.
- Despite ONC212 showing effectiveness in inducing cell death in cancer cells like HeLa and A549, its specific mechanisms are still not fully understood.
- The study reveals that ONC212 triggers apoptotic features without typical mitochondrial changes and can enhance cell death when combined with a Bcl-2/Bcl-xL inhibitor, indicating its potential for use in combination therapies for tumors with impaired mitochondrial signaling.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) emerged in December 2019, causing a range of respiratory infections from mild to severe. This resulted in the ongoing global COVID-19 pandemic, which has had a significant impact on public health. The World Health Organization declared COVID-19 as a global pandemic in March 2020.
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