Publications by authors named "Yaming Ji"
Article Synopsis
- Resistance to immunotherapy in colorectal cancer (CRC) is linked to the enzyme PFKFB3, which is found at higher levels in CRC tissues compared to normal ones.
- Research shows that inhibiting PFKFB3 can reduce tumor growth and is associated with several cancer-related pathways and immune responses.
- High expression of PFKFB3 is tied to immunotherapy resistance, particularly in patients resistant to PD-L1 blockade, highlighting its potential as a therapeutic target to improve treatment outcomes.
Objective: The current research aimed to development and validation in signature immune genes for lymphatic metastasis in papillary thyroid cancer (PTC).
Method: Weighted correlation network analysis (WGCNA) was performed to identify genes closely correlated with lymphatic metastasis in PTC from TCGA database. Information on immune-related genes (IRGs) was obtained from the ImmPort database.
Gastric cancer (GC) is one of the most aggressive malignant tumors with low early diagnosis and high metastasis. Despite progress in treatment, to combat this disease, a better understanding of the underlying mechanisms and novel therapeutic targets is needed. KIF23, which belongs to the KIF family, plays a vital role in various cell processes, such as cytoplasm separation and axon elongation.
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