Large-scale multicenter study reveals anticitrullinated SR-A peptide antibody as a biomarker and exacerbator for rheumatoid arthritis.

Current diagnosis and treatment of rheumatoid arthritis (RA) is still challenging. More than one-third of patients with RA could not be accurately diagnosed because of lacking biomarkers. Our recent study reported that scavenger receptor-A (SR-A) is a biomarker for RA, especially for anticyclic citrullinated peptide antibody (anti-CCP)-negative RA.

The emerging roles of miRNA-mediated autophagy in ovarian cancer.

Ovarian cancer is one of the common tumors of the female reproductive organs. It has a high mortality rate, is highly heterogeneous, and early detection and primary prevention are very complex. Autophagy is a cellular process in which cytoplasmic substrates are targeted for degradation in lysosomes through membrane structures called autophagosomes.

Stochastic analysis of COVID-19 by a SEIR model with Lévy noise.

We propose a Lévy noise-driven susceptible-exposed-infected-recovered model incorporating media coverage to analyze the outbreak of COVID-19. We conduct a theoretical analysis of the stochastic model by the suitable Lyapunov function, including the existence and uniqueness of the positive solution, the dynamic properties around the disease-free equilibrium and the endemic equilibrium; we deduce a stochastic basic reproduction number R for the extinction of disease, that is, if R ≤1, the disease will go to extinction. Particularly, we fit the data from Brazil to predict the trend of the epidemic.