Publications by authors named "Yameng Fang"
Fish Shellfish Immunol
November 2023
Article Synopsis
- KCMF1 is an E3 ubiquitin ligase involved in several biological processes in mammals, but its role in invertebrates, particularly the mud crab Scylla paramamosian, is less understood.
- Real-time PCR analysis indicates that a KCMF1-like gene is widely expressed in various crab tissues, especially in muscle and mid-intestine, and is up-regulated in response to white spot syndrome virus infection.
- RNA interference of KCMF1-like shows that its knockdown increases viral proliferation and affects hemocyte apoptosis, suggesting it plays an essential role in the antiviral immune defense of mud crabs.
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