Comparative analysis of the risk of severe bacterial infection and septicemia in adolescents and young adults with treatment-resistant depression and treatment-responsive depression - a nationwide cohort study in Taiwan.

Previous studies have shown an association between depression and increased susceptibility to infection in the general population. However, there has been no prior research specifically examining the relationship between treatment-resistant depression (TRD) and severe bacterial infections (SBI) in adolescents and young adults. This retrospective observational cohort study utilized the Taiwan National Health Insurance Research Database (NHIRD) from 2001 to 2010.

Virtual reality technology improves the gait and balance function of the elderly: a meta-analysis of randomized controlled trials.

Introduction: Improving the gait and balance function is an important part of the health of the elderly. This study aimed to conduct a meta-analysis to evaluate the effects of virtual reality (VR) technology on the gait and balance function of the elderly.

Material And Methods: Two authors independently searched EMBASE, PubMed, Web of Science, ClinicalTrials, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang and Weipu databases up to October 20, 2023 for randomized controlled trials (RCTs) on the application of VR in improving the gait and balance function in the elderly.

Social isolation and depressive symptoms among chinese older adults: Serial mediating roles of social support and resilience.

Background: Social isolation is a significant risk factor for depressive symptoms in older adults, with social support and resilience serving as protective factors. However, the mechanisms underlying this association are not well understood.

Methods: A cross-sectional survey was performed of 1020 participants (aged ≥ 60years) in the northern, central and southern parts of Jiangsu Province, China.

Predicting nursing workload in digestive wards based on machine learning: A prospective study.

Background: The process of assessing and allocating nursing staff, as well as evaluating performance, relies heavily on nursing workload, which is strongly associated with patient safety outcomes. Nevertheless, most previous studies have utilized cross-sectional data collection methods, which limit the precision of workload prediction. Static workload models do not incorporate longitudinal changes in influential factors, potentially resulting in delayed or erroneous nursing management decisions and ultimately causing imbalances in nurses' workload.

Resistance to antidepressant treatment among patients with major depressive disorder: a nationwide study.

Treatment-resistant depression (TRD) has great clinical importance because it has the highest disability burden of all depressive conditions. We investigated the prevalence of TRD and identified the risk and protective factors associated with antidepressant resistance among adult patients with major depressive disorder (MDD). A total of 176 132 adult patients with MDD were selected from the Taiwan National Health Insurance Research Database between 2001 and 2010 and followed for 1 year.

Parental mental disorders and ages of onset of severe mental disorders in offspring: A nationwide family-link study.

Objective: The current study used a retrospective study design to investigate the association between age of onset of severe mental disorders in offspring and the likelihood of diagnoses of parental mental disorder.

Method: We enrolled 212,333 people with severe mental disorder, including schizophrenia, bipolar disorder (BD), or major depressive disorder (MDD) and 2,123,329 controls matched for age, sex, and demographics from the National Health Insurance Database of Taiwan. Poisson regression models were used to examine the likelihood of diagnoses of five mental disorders in their parents compared to the parents of the controls (reported as odds ratio (OR) with 95% confidence interval), including schizophrenia, BD, MDD, alcohol use disorder (AUD), and substance use disorder (SUD).

Brain functional networks and structures that categorize type 2 bipolar disorder and major depression.

Background: Distinguishing between type 2 bipolar disorder (BD II) and major depressive disorder (MDD) poses a significant clinical challenge due to their overlapping symptomatology. This study aimed to investigate neurobiological markers that differentiate BD II from MDD using multimodal neuroimaging techniques.

Methods: Fifty-nine individuals with BD II, 114 with MDD, and 117 healthy controls participated in the study, undergoing structural and functional magnetic resonance imaging.

Thalamocortical Dysconnectivity in Treatment-Resistant Depression.

Thalamocortical connectivity is associated with cognitive and affective processing. The role of thalamocortical connectivity in the pathomechanism of treatment-resistant depression (TRD) remains unclear. This study included 48 patients with TRD and 48 healthy individuals.

Nutrients, Diet Quality, and Dietary Patterns in Patients with Inflammatory Bowel Disease: A Comparative Analysis.

(1) Background: Diet plays an important role in the development of inflammatory bowel disease (IBD). There are a number of methods available to assess the diets of patients with IBD, including nutrients, dietary patterns, and various appraisal tools of diet quality. However, research on diet quality and dietary patterns in IBD populations is limited, and comparative evaluations of dietary intake in patients with IBD have not been performed.

Familial coaggregation of major psychiatric disorders and neurodevelopmental disorders among first-degree relatives of individuals with generalized anxiety disorder.

Background: Anxiety disorders, major psychiatric disorders (e.g., schizophrenia and major affective disorders), and neurodevelopmental disorders (e.

Congenital hypothyroidism and risk of subsequent autism spectrum disorder and attention-deficit/hyperactivity disorder in Taiwan.

Aim: Evidence suggests an association between maternal hypothyroidism and risk of attention-deficit/hyperactivity disorder (ADHD) or autism spectrum disorder (ASD) in offspring. We examined the risk of ASD and ADHD in individuals with congenital hypothyroidism (CHT).

Methods: A nationwide population-based cohort study enrolled a total of 1260 children younger than 12 years with a confirmed diagnosis of CHT and no prior diagnosis of any neurodevelopmental disorders, selected from the National Health Insurance Research Database of Taiwan between 1998 to 2013.

Risk of Periodontitis in Adolescents With Attention Deficit Hyperactivity Disorder: A Cohort Study of 81,055 Participants.

Objectives: Previous studies have demonstrated poor oral hygiene in children with attention deficit hyperactivity disorder (ADHD). However, the association between ADHD and periodontitis is still unclear.

Methods: In all, 16,211 adolescents with ADHD and 162,110 age- and sex-matched controls participated in the study between 2001 and 2011.

Ethical risks in robot health education: A qualitative study.

Background: As health education robots may potentially become a significant support force in nursing practice in the future, it is imperative to adhere to the European Union's concept of "Responsible Research and Innovation" (RRI) and deeply reflect on the ethical risks hidden in the process of intelligent robotic health education.

Aim: This study explores the perceptions of professional nursing professionals regarding the potential ethical risks associated with the clinical practice of intelligent robotic health education.

Research Design: This study adopts a descriptive phenomenological approach, employing Colaizzi's seven-step method for data analysis.