Publications by authors named "Yaman Chen"
(+)-Ambrein is the primary component of ambergris, a rare product found in sperm whales (Physeter microcephalus). Microbial production using sustainable resources is a promising way to replace animal extraction and chemical synthesis. We constructed an engineered yeast strain to produce (+)-ambrein de novo.
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- Artemisia argyi is a medicinal plant known for its health benefits due to its various triterpenoids that have anti-viral, anti-cancer, and anti-oxidant properties.
- The study focuses on isolating and identifying four genes related to the 2,3-oxidosqualene cyclase (OSC) family, which are crucial for the triterpenoid biosynthesis pathway in A. argyi.
- Three of the isolated OSC genes were shown to produce different triterpenoids through a yeast expression system, enhancing knowledge of how these valuable compounds are synthesized in the plant.