High-Density Donor-Acceptor Pair Mediated Carrier Transport Dynamics for Hydrogen Production Performance Promotion Based on Nonstoichiometric Quantum Dots.

Ternary I-III-VI semiconductors are useful light-capture materials, but the presence of a special donor-acceptor pair complicates the dynamics of carriers in the photocatalytic process, and the combined effect of multiple types of defects makes it difficult to study the single type of defect on carrier dynamics. Here, excess inorganic S ligand is used to passivate the surface defects of the nonstoichiometric ratio Ag-In-Zn-S quantum dots (QDs), which enables the systematic investigation of the effects of high-density donor-acceptor pairs on the carrier separation and transfer path during photocatalysis. The results show that the donor-acceptor pair defects in quantum dots can effectively separate the carriers because the defects generated by the donor or acceptor can effectively "store" the carriers at the fixed energy level and provide an additional path for the transfer of the carriers.

Characterization, physicochemical properties, antioxidant activity and hypolipidemic activities of a polysaccharides from Lachnum YM40.

LEP-1a, a new polysaccharide fraction isolated and purified from Lachnum YM40, has a molecular weight of 24.29 kDa. LEP-1a's chemical composition investigation showed that mannose, galactose, and glucose made up the majority of its cosmetics.

Chitosan-Based Charge-Controllable Supramolecular Carrier for Universal Immobilization of Enzymes with Different Isoelectric Points.

Electrostatic adsorption is an enzyme immobilization method that effectively maintains enzyme activity and exhibits considerable binding efficiency. However, enzymes carry different charges at their respective reaction pH levels, which prevents the use of the same carrier to immobilize enzymes with different charges. In this study, we employed a template-mediated polysaccharide-enzyme coupling self-assembly strategy to develop a charge-controllable supramolecular immobilization carrier by regulating the charge properties of carboxymethyl chitosan, enabling the universal immobilization of enzymes with different charge levels across a range of reaction pH values.

Efficient roller-driven elastocaloric refrigerator.

Elastocaloric cooling has experienced fast development over the past decade owing to its potential to reshape the refrigeration industry. While the solid-state elastocaloric refrigerant is emission-free, the efficiency of the state-of-the-art elastocaloric cooling systems is not sufficient yet to reduce carbon emissions during operation. In this study, we double the coefficient of performance, the most commonly used efficiency metric, via the synergy of material-level advances in TiNiCu and the system-level roller-driven mechanism capable of recovering kinetic energy.

Copper Atom Pairs Stabilize *OCCO Dipole Toward Highly Selective CO Electroreduction to CH.

Deeply electrolytic reduction of carbon dioxide (CO) to high-value ethylene (CH) is very attractive. However, the sluggish kinetics of C-C coupling seriously results in the low selectivity of CO electroreduction to CH. Herein, we report a copper-based polyhedron (Cu2) that features uniformly distributed and atomically precise bi-Cu units, which can stabilize *OCCO dipole to facilitate the C-C coupling for high selective CH production.

Macro-characteristics and micro-mechanisms of NaSO precipitation dissolved by KNO molten salt in a continuous supercritical water system.

This work aims to explore the ability of molten salt to solve salt deposition in supercritical water (SCW) related technologies including supercritical water oxidation and supercritical water gasification, with KNO and NaSO as examples. In the pure KNO solution, the two-phase layering of high-density KNO molten salt (settling at the reactor bottom) and low-density saturated KNO-SCW salt solution (flowing out at the top outlet of the reactor) was formed in a kettle-reactor with about 6.5 ratio of depth to inner diameter, thereby improving the accuracy of measured solubilities.

Polygenic Risk Score Modifies the Association of HbA1c With Hearing Loss in Middle-Aged and Older Chinese Individuals: The Dongfeng-Tongji Cohort.

Objective: Evidence regarding the modifying effect of the polygenic risk score (PRS) on the associations between glycemic traits and hearing loss (HL) was lacking. We aimed to examine whether these associations can be influenced by genetic susceptibility.

Research Design And Methods: This cross-sectional study included 13,275 participants aged 64.

Diversity of Arbuscular Mycorrhizal Fungi of the Rhizosphere of L. from Four Main Producing Areas in Northwest China and Their Effect on Plant Growth.

Arbuscular mycorrhizal fungi (AMF) can help plants absorb more mineral nutrients after they colonize plant roots, and the mycelia harmonize the soil structure and physical and chemical properties by secreting compounds. AMF species co-evolve with their habitat's geographic conditions and hosts; this gradually causes differences in the AMF species. By using Melzer's reagent to analyze the morphology and using Illumina Miseq sequencing technology to perform the molecular identification of AMF communities among the four typical planting areas (Zhongning, Guyuan, Jinghe, and Dulan) investigated, the variety of roots and rhizosphere AMF communities was greater in the Zhongning area, and every region additionally had endemic species.

Commercializable Naphthalene Diimide Anolytes for Neutral Aqueous Organic Redox Flow Batteries.

Neutral aqueous organic redox flow batteries (AORFBs) hold the potential to facilitate the transition of renewable energy sources from auxiliary to primary energy, the commercial production of anolyte materials still suffers from insufficient performance of high-concentration and the high cost of the preparation problem. To overcome these challenges, this study provides a hydrothermal synthesis methodology and introduces the charged functional groups into hydrophobic naphthalene diimide cores, and prepares a series of high-performance naphthalene diimide anolytes. Under the synergistic effect of π-π stacking and H-bonding networks, the naphthalene diimide exhibits excellent structural stability and the highest water solubility (1.

Image-Guided Photothermal and Immune Therapy of Tumors via Melanin-Producing Genetically Engineered Bacteria.

Photothermal therapy (PTT) is a new treatment modality for tumors. However, the efficient delivery of photothermal agents into tumors remains difficult, especially in hypoxic tumor regions. In this study, an approach to deliver melanin, a natural photothermal agent, into tumors using genetically engineered bacteria for image-guided photothermal and immune therapy is developed.

Predicting co-liquefaction bio-oil of sewage sludge and algal biomass via machine learning with experimental optimization: Focus on yield, nitrogen content, and energy recovery rate.

Machine learning (ML), a powerful artificial intelligence tool, can effectively assist and guide the production of bio-oil from hydrothermal liquefaction (HTL) of wet biomass. However, for hydrothermal co-liquefaction (co-HTL), there is a considerable lack of application of experimentally verified ML. In this work, two representative wet biomasses, sewage sludge and algal biomass, were selected for co-HTL.

Associations of Long-Term Exposure to PM and Its Constituents with Erythrocytosis and Thrombocytosis in Rural Populations.

Evidence on the effect of long-term exposure to fine particulate matter (PM) on erythrocytosis and thrombocytosis prevalence was limited. We aimed to investigate the association of PM and its constituents with the risks of erythrocytosis and thrombocytosis. The present study included a total of 33,585 participants from the Henan Rural Cohort at baseline between 2015 and 2017.

Association between snoring, daytime sleepiness and cardiovascular disease in Chinese rural adults.

Backgrounds And Aims: Evidence on the association between habitual snoring, excessive daytime sleepiness (EDS), and cardiovascular diseases (CVDs) remains uncertain and limited. The study aimed to explore the independent and joint association between habitual snoring, EDS, and CVDs in rural Chinese adults.

Methods And Results: A total of 28,140 participants from the Henan rural cohort study were included.

Biosynthetic Melanin/Ce6-Based Photothermal and Sonodynamic Therapies Significantly Improved the Anti-Tumor Efficacy.

Photothermal therapy (PTT) and sonodynamic therapy (SDT) are becoming promising therapeutic modalities against various tumors in recent years. However, the single therapeutic modality with SDT or PTT makes it difficult to achieve a satisfactory anti-tumor outcome due to their own inherent limitations, such as poor tissue penetration for the near-infrared (NIR) laser and the limited cytotoxic reactive oxygen species (ROS) generated from conventional sonosensitizers irradiated by ultrasound (US). Here, we successfully biosynthesized melanin with a controllable particle size with genetically engineered bacteria harboring a heat-inducible gene circuit.

Independent and Combined Associations of Sleep Duration, Bedtime, and Polygenic Risk Score with the Risk of Hearing Loss among Middle-Aged and Old Chinese: The Dongfeng-Tongji Cohort Study.

Evidence available on the independent and combined associations of sleep duration, bedtime, and genetic predisposition with hearing loss was lacking. The present study included 15,827 participants from the Dongfeng-Tongji cohort study. Genetic risk was characterized by polygenic risk score (PRS) based on 37 genetic loci related to hearing loss.

Disease Burden and the Accumulation of Multimorbidity of Noncommunicable Diseases in a Rural Population in Henan, China: Cross-sectional Study.

Background: Multimorbidity causes substantial disease and economic burdens on individuals and the health care system.

Objective: This study aimed to explore the disease burden of multimorbidity and the potential correlations among chronic noncommunicable diseases (NCDs) in a rural population in Henan, China.

Methods: A cross-sectional analysis was performed using the baseline survey of the Henan Rural Cohort Study.

Integerrima A-E, phenylethanoid glycosides from the stem of Callicarpa integerrima.

Five new phenylethanoid glycosides integerrima A-E (1-5) were isolated from the stem of Callicarpa integerrima for the first time. Their structures were elucidated by extensive spectroscopic analyses. In addition, cytotoxicity, anti-adipogenic and antioxidant activities were evaluated.

Prevention of the Lachnum polysaccharide and its selenium derivatives on cisplatin-induced acute kidney injury in mice.

To investigate the renal protective effects of the polysaccharide LEP-1a and derivatives of selenium (SeLEP-1a) from Lachnum YM38, cisplatin (CP) was used to establish an acute kidney model. LEP-1a and SeLEP-1a could effectively reverse the decrease in renal index and improved renal oxidative stress. LEP-1a and SeLEP-1a significantly reduced the contents of the inflammatory cytokines.

Prevalence and morphological subtype distributions of anaemia in a Chinese rural population: the Henan Rural Cohort study.

Objective: This study aimed to evaluate the recent prevalence and the distributions of morphological subtypes of anaemia in the rural population.

Design: Anaemia was defined according to the WHO and the Chinese criteria, and the morphological subtypes of anaemia were classified based on the erythrocyte parameters. The age-standardised prevalence was calculated according to the data of the Population Census 2010 in China.

Response of fermentation quality and microbial community of oat silage to homofermentative lactic acid bacteria inoculation.

Oat ( L.) is one of the important forage crops in the world. However, oat grown in Southwest China has higher moisture content and their preservation face significant challenges.

In Situ Transition Layer Design Based on Ti Additive Enabling High-Performance Liquid Metal Batteries.

Liquid metal batteries (LMBs), with the merits of long lifespan and low cost, are deemed as one of the most promising energy storage technologies for large-scale energy storage applications due to the use of liquid metal electrodes and molten salt electrolytes. However, the consequent problem is that the poor wettability between graphite-based collectors and the liquid metal/alloy electrodes leads to large contact resistance, which limits the efficiency and stability of the battery. In this work, a transition layer in situ formed on a graphite-based positive electrode current collector by Ti additive is designed for the first time, which increases the wettability between the positive alloy and the current collector and improves the voltage efficiency of the Li||Sb-Sn cell from 85.

Kitchen ventilation attenuated the associations of solid fuel use and long duration for cooking with the increased prevalence of normocytic anemia.

Evidence on the potential risk factors of normocytic anemia, the most prevalent morphology subtype of anemia, was scarce to date. The purpose of this study is to investigate the association of cooking fuel use or daily cooking duration with normocytic anemia and further explore the modification effect of mechanical ventilation. Participants totaling 29,448 from the Henan Rural Cohort were included in this study.

Biosynthesis of Melanin Nanoparticles for Photoacoustic Imaging Guided Photothermal Therapy.

Photothermal therapy (PTT) has attracted considerable attention in recent years due to their unique advantages in minimal invasiveness and spatiotemporal selectivity. However, the fabrication procedures of PTT agents frequently require complex chemical and/or physical methods that involves harsh and environmentally hazardous conditions. Here, a genetically engineered bacterium is developed to synthesize melanin nanoparticles under mild and environmentally friendly conditions.

Acidity/carbon dioxide-sensitive triblock polymer-grafted photoactivated vesicles for programmed release of chemotherapeutic drugs against glioblastoma.

Controllable release of chemotherapeutic drugs in tumor sites remains a big challenge for precision therapy. Herein, we developed acidity/carbon dioxide (H/CO)-sensitive poly (ethylene glycol)-b-poly (2-(diisopropylamino) ethyl methacrylate)-b-polystyrene triblock polymer (PEG-b-PDPA-b-PS) grafted photoactivated vesicles for programmed release of chemotherapeutic drugs against glioblastoma. In brief, gold nanoparticles (GNPs) were firstly tethered with the H/CO-sensitive PEG-b-PDPA-b-PS polymer.

Relationship of miRNA‑126 and miRNA‑122 expression with type 2 diabetes mellitus and related glucose metabolism parameters: A systematic review and meta‑analysis.

There are increasing numbers of studies investigating the potential link between microRNAs (miRNAs) and type 2 diabetes mellitus (T2DM) risk. Based on the prior evidence and the differentially expressed candidate plasma exosome miRNAs in our established discovery study, the current meta-analysis studied miR-126 and miR-122 specifically. The purpose of the present study was to systematically and quantitatively evaluate the relationship of miR-126 and miR-22 expression level with T2DM risk as well as related glucose metabolism parameters.