Publications by authors named "Yali Yu"

(Jordan, 1898), a beetle species of ecological and ornamental significance, is predominantly found in southern China. With limited dispersal ability, it is classified as a Class 2 protected species in China. In this study, the widely employed maximum entropy (MaxEnt) model and the ensemble Biomod2 model were applied to simulate habitat suitability in China under current environmental conditions based on available distribution data and multiple environmental variables.

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Two new species of ambrosia beetles Xylosandrus Reitter, 1913 (Scolytinae: Xyleborini), Xylosandrus luokengensis Lin & Gao sp. nov. and Xylosandrus nanlingensis Lin & Gao sp.

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Optical logic operation is promising for ultrafast information processing and optical computing due to the high computation speed and low power consumption. However, conventional optical logic devices require either a complex structure and circuit design or a constant voltage supply, which impedes the development of high-density integrated circuits. Here, all-optical logic devices are designed using a self-powered polarization-sensitive photodiode of the GeSe homojunction, which is attributed to an anisotropic band structure and built-in electric field.

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  • Mesenchymal stem cells (MSCs) are promising for regenerative therapies, but their natural aging (senescence) limits the quantity and quality available for treatment.* -
  • A new culture plate made from a piezoelectric β-poly(vinylidene fluoride) film was developed, which effectively combats MSC senescence and improves important markers related to their quality and functioning.* -
  • This innovative method not only enhances MSC properties for potential clinical use but also supports better wound healing in experimental models by rejuvenating the cells through improved mitochondrial function.*
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Osteoarthritis (OA) is a comprehensive joint disorder. The specific genes that trigger OA and the strategies for its effective management are not fully understood. This study focuses on identifying key genes linked to iron metabolism that could influence both the diagnosis and therapeutic approaches for OA.

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In this study, the structural characteristics, functional properties, and in vitro gastrointestinal digestibility of glutenin from Tiger nut seed meal (TNSMG) treated by microwave (140-700 W, 20-60 s) and water-bath heating (40-100 °C, 10-30 min) were investigated. Analysis of the surface hydrophobicity, intrinsic fluorescence spectroscopy and Fourier transform infrared spectroscopy indicated that both microwave and water-bath heating treatments caused structure changes of TNSMG. The results showed an increase in the exposure of sulfhydryl groups and the content of β-sheet, coupled with a decrease in the content of α-helix and β-turn.

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Band alignment engineering is crucial for facilitating charge separation and transfer in optoelectronic devices, which ultimately dictates the behavior of Van der Waals heterostructures (vdWH)-based photodetectors and light emitting diode (LEDs). However, the impact of the band offset in vdWHs on important figures of merit in optoelectronic devices has not yet been systematically analyzed. Herein, the regulation of band alignment in WSe/BiTe Se vdWHs (0 ≤ x ≤ 3) is demonstrated through the implementation of chemical vapor deposition (CVD).

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  • USP52, a member of the deubiquitinase family, plays a critical role in colorectal cancer (CRC) by influencing immunotherapy effectiveness and immune evasion, suggesting a need for more research into its effects on patient outcomes.
  • Analysis of public databases revealed that USP52 is significantly overexpressed in CRC tissues, correlating with poor patient prognosis and a suppressed immune environment characterized by low immune cell infiltration.
  • The study highlights that high levels of USP52 are linked to reduced responsiveness to immunotherapy and chemotherapeutic drugs, along with a negative relationship to tumor mutation burden (TMB) and microsatellite instability (MSI), emphasizing its potential as a target for CRC therapy improvements.
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Beetles have a remote evolutionary history dating back to the Carboniferous, with Mesozoic fossils playing a pivotal role in elucidating the early evolution of extant families. Despite their exceptional preservation in amber, deciphering the systematic positions of Mesozoic trogossitid-like beetles remains challenging. Here, we describe and illustrate a new trogossitid-like lineage from mid-Cretaceous Kachin amber, Li, Kolibáč, Liu & Cai, gen.

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Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have obvious advantages over MSC therapy. But the strong procoagulant properties of MSC-EVs pose a potential risk of thromboembolism, an issue that remains insufficiently explored. In this study, we systematically investigated the procoagulant activity of large EVs derived from human umbilical cord MSCs (UC-EVs) both in vitro and in vivo.

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  • The study investigates the role of USP21, a member of the ubiquitin-specific proteases family, in colorectal cancer (CRC) and its impact on host immunity.
  • It was found that higher levels of USP21 are associated with worse patient prognosis, increased cancer cell growth and migration, and a less favorable tumor microenvironment (TME) for immune activation.
  • Conversely, lower USP21 levels correlate with enhanced immune responses, higher tumor mutation rates, and a better response to immunotherapy and chemotherapy, highlighting its potential as a therapeutic target in CRC.
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  • * Researchers are focusing on improving photodetectors that can perform real-time computations and handle various functions simultaneously at the sensor level.
  • * This study introduces a unique p-type semiconductor called GaTeSe, which allows for three-band imaging and real-time image processing by utilizing polarization-sensitive photocurrents across a wavelength range of 390-810 nm.
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  • * The trial involved 200 patients, with one group receiving TCM granules alongside standard treatment and the control group receiving a placebo; assessments were made over a year to evaluate symptoms, lung function, and quality of life.
  • * Results showed that TCM treatment significantly improved outcomes in symptoms, lung function (FVC% and FEV1), and quality of life, indicating its potential as a beneficial addition to standard COPD therapy.
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Introduction: Quercetin (Qc), rutin (Ru), and hyperoside (Hyp) are three common polyphenols widely distributed in the plant kingdom.

Method: This study explored the inhibition and mechanisms of Qc, Ru, and Hyp against xanthine oxidase (XOD) by enzyme kinetic analysis, fluorescence analysis, and molecular docking. The inhibitory activities of the three polyphenols on XOD showed the following trend: quercetin > hyperoside > rutin, with IC50 values of 8.

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Protein from tiger nut meal (TNP) performance high nutritional value. This study optimized the extraction parameters for TNP (DES-TNP) using deep eutectic solvent, with HBD: HBA = 5:1, Liquid: Solid = 11:1, and the moisture content was 15 %. A comprehensive comparison was conducted with the protein extracted using alkali-soluble acid precipitation (ASAE-TNP).

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Remote sensing technology, which conventionally employs spectrometers to capture hyperspectral images, allowing for the classification and unmixing based on the reflectance spectrum, has been extensively applied in diverse fields, including environmental monitoring, land resource management, and agriculture. However, miniaturization of remote sensing systems remains a challenge due to the complicated and dispersive optical components of spectrometers. Here, m-phase GaTeSe with wide-spectral photoresponses (250-1064 nm) and stack it with WSe are utilizes to construct a two-dimensional van der Waals heterojunction (2D-vdWH), enabling the design of a gate-tunable wide-spectral photodetector.

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Type 2 alveolar epithelial cell (AEC2) senescence is crucial to the pathogenesis of pulmonary fibrosis (PF). The nicotinamide adenine dinucleotide (NAD)-consuming enzyme cluster of differentiation 38 (CD38) is a marker of senescent cells and is highly expressed in AEC2s of patients with PF, thus rendering it a potential treatment target. Umbilical cord mesenchymal stem cell (MSC)-derived extracellular vesicles (MSC-EVs) have emerged as a cell-free treatment with clinical application prospects in antiaging and antifibrosis treatments.

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This study revealed the variations in odor characteristics and underlying mechanisms of different cross-linked surimi gels under liquid nitrogen (LN) spray freezing. The results demonstrated that LN spray freezing had an essential effect on the gels' odor. The odor changes in the -80 °C LN spray freezing group were closer to the control group, while -35 °C LN spray freezing treatment had the greatest impact on the aroma quality of gels.

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IgA nephropathy (IgAN) is an immune-mediated glomerulonephritis, posing a challenge for the long-term management. It is crucial to monitor the disease's activity over the disease course. Crescent lesions have been known as an active lesion associated with immune activity.

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Solid materials with ultra-low thermal conductivity () are of great interest in thermoelectrics for energy conversion or as thermal barrier coatings for thermal insulation. Many low- materials exhibit unique properties, such as weak or even insignificant dependence on temperature () for , , an anomalous glass-like behavior. However, a comprehensive theoretical model elucidating the microscopic phonon mechanism responsible for the glass-like - relationship is still absent.

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Red swamp crayfish, (), is an important model crustacean organism used in many types of research. However, the effects of different doses of aminomethylphosphonic acid (AMAP) on the transcriptome and metabolites of have not been explored. Thus, this study investigated the molecular and metabolic mechanisms activated at the different exposure dosages of AMAP in to provide new insights into the strategies of in response to the high concentrations of AMAP in the environment.

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Background: Epigenetics plays an important role in the pathogenesis of inflammatory bowel disease (IBD). Some studies have reported that YAP is involved in inflammatory response and can regulate target genes through epigenetic modifications. JMJD3, a histone H3K27me3 demethylase, is associated with some inflammatory diseases.

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  • Patients with allergic bronchopulmonary aspergillosis (ABPA) complicating asthma often experience frequent acute exacerbations and hospitalizations despite standard therapies.
  • A study evaluated the effectiveness and safety of omalizumab in 26 adult patients over a year, revealing significant reductions in both glucocorticoid and antifungal medication dosages after treatment.
  • The results indicated that omalizumab significantly lowered the frequency of exacerbations and daily glucocorticoid use, suggesting it may be a beneficial treatment option for this patient group, potentially influenced by factors like age and BMI.
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In this study, the bighead carp () was the object of research to compare and analyze the contents of conventional nutrients, amino acids, fatty acids, inosinic acid, and earthy-smelling compounds (geosmin and 2-methylisoborneol) in muscles of its dorsal, belly, tail, opercula, eye socket, and mandible in order to evaluate their quality. The findings could inform recommendations for the consumption and processing of different muscle parts of the bighead carp. The results showed that the water content in the abdominal muscle was significantly lower than that in other parts, and the crude fat content was significantly higher than that in other parts ( < 0.

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