Publications by authors named "Yalcin A"

IntroductionPeripheral artery disease (PAD) poses a growing clinical challenge due to an aging population, despite advances in treatment methods. Various scoring systems have emerged to predict high-risk patients, including the HALP (hemoglobin, albumin, lymphocyte, and platelet) score, known for predicting prognosis in cancers and stroke. This study assesses the HALP score's relation to lesion severity and long-term mortality in PAD patients.

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Aim: The aim of this study was to determine the amount of displacement of the Center of Pressure (CoP) during movement of the affected limb in children with Neonatal Brachial Plexus Palsy (NBPP) and to compare it with the unaffected side.

Method: Forty-six children (6.63 ± 1.

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Purpose: Idiopathic normal-pressure hydrocephalus (iNPH) presents with Hakim's triad and diagnosis is solely based on clinical findings. The role of imaging is confined to the detection of ventriculomegaly and the exclusion of other possible entities. Hyperdynamic CSF flow has been demonstrated in various flow-related imaging studies.

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Objectives: The present study aimed to examine mood disorders in patients discharged from the hospital due to Coronavirus Disease-19 (COVID-19).

Methods: The study included patients who were admitted to Akdeniz University with the diagnosis of COVID-19. Post-Traumatic Stress Disorder (PTSD) Checklist - Civilian Version (PCL-5), and Beck Anxiety and Depression Inventories were administered to the patients at least 30 days after discharge.

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Colic is a leading cause of mortality in horses, demanding precise and timely interventions. This study integrates machine learning and explainable artificial intelligence (XAI) to predict survival outcomes in horses with colic, using clinical, procedural, and diagnostic data. Random forest and XGBoost emerged as top-performing models, achieving F1 scores of 85.

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Objectives: This study aimed to investigate the potential effects of different doses of essential oil (Lavender EO) administered by inhalation on sleep latency and neuromodulators regulating the sleep/wake cycle in rats with total sleep deprivation (TSD).

Materials And Methods: Forty-eight male Sprague-Dawley rats were divided into five groups: Control, Alprazolam (ALP, 0.25 mg/kg given intraperitoneally), L1 (Lavender EO, 0.

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Background: In this multicenter study we aimed to retrospectively identify the midterm clinical outcomes of the mini-crush technique (MCT) and nano-crush technique (NCT) in patients with complex bifurcation lesions (CBLs).

Methods: The study included 431 patients (318 men [73.8%], mean age 60.

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Article Synopsis
  • The study aimed to explore the connection between serum antidrug antibodies (ADAbs), hypersensitivity reactions, and local injection site reactions in patients with ankylosing spondylitis and rheumatoid arthritis who were on anti-TNF treatments.
  • Sixty-nine patients with ankylosing spondylitis and 46 with rheumatoid arthritis were evaluated, measuring their drug levels, disease activity scores, and conducting skin tests to assess hypersensitivity.
  • Results indicated a significant link between hypersensitivity reactions (both immediate and local) and the intradermal tests in patients taking anti-TNF drugs, particularly with adalimumab and etanercept.
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Objectives: Chronic limb-threatening ischemia (CLTI) is the most severe manifestation of peripheral artery disease (PAD) and is associated with high morbidity and mortality. The Naples prognostic score (NPS), a composite marker incorporating serum albumin, total cholesterol, neutrophil-to-lymphocyte ratio (NLR), and lymphocyte-to-monocyte ratio (LMR), has shown prognostic value in various cardiovascular conditions. This study aimed to evaluate the prognostic significance of the NPS in predicting all-cause mortality and any kind of amputation in patients with CLTI undergoing endovascular treatment (EVT) for below-the-knee (BTK) lesions.

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Lithium-rich layered oxide materials (Li-NMC) are considered a potential cathode material for next-generation batteries, thanks to their high theoretical specific capacity. Large potential drop and capacity loss after long cycles are the main obstacles to expanding commercial utilization of Li-NMC. In the past decade, great efforts have been made to overcome those issues of Li-NMCs.

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  • The study investigates the neuroprotective effects of Thymoquinone (TQ) and Metformin (MM) on Parkinson's disease by testing their effects separately and in combination on mice.* -
  • Mice treated with TQ, MM, or both showed significant improvements in motor coordination and reduced markers of oxidative stress and neurodegeneration compared to the control group.* -
  • Findings suggest that TQ and MM together may be more effective than either alone, providing evidence for their potential as a therapy for Parkinson's disease.*
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  • The study investigates the levels of α-Klotho, a protein with neuroprotective properties, in patients with Parkinson's Disease (PD) compared to healthy controls.
  • Results show that PD patients have significantly lower serum α-Klotho levels (0.85 nmol/L) than controls (1.47 nmol/L), with a notable decrease in those with dementia.
  • The research indicates α-Klotho might be a potential biomarker for PD, but further studies are necessary to validate these results.
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Background: Double-kissing (DK) crush and DK culotte are the recommended 2-stent strategies in true coronary bifurcation lesions. However, it is a matter of curiosity about which of the DK crush and DK culotte stenting techniques will have superior results. We aimed to compare the clinical outcomes of DK crush and DK culotte stenting in nonleft main coronary artery bifurcation.

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Purpose: To determine the efficacy and safety of virtual unenhanced imaging by comparing the attenuation values of virtual and true unenhanced images acquired using third-generation dual-source dual-energy computed tomography (dsDECT).

Methods: Single-energy non-contrast and dual-energy arterial and venous phase images of 97 patients who underwent triphasic abdominal computed tomography (CT) were included in this retrospective study. Virtual unenhanced images were generated for the arterial (a) and venous (v) phases using two dsDECT algorithms.

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  • A study evaluated the effectiveness of three screening tools for identifying sarcopenia (muscle loss) in hospitalized older adults: SARC-F, SARC-CalF, and the Ishii tests.
  • The research involved 204 hospitalized individuals, assessing muscle mass, strength, and physical performance according to established criteria.
  • Results showed that SARC-CalF had the highest sensitivity and specificity, making it the most reliable tool for detecting sarcopenia, while the Ishii test had high sensitivity but low specificity.
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Unlabelled: Hand use varies according to which brain hemisphere is dominant. Early androgen exposure causes right hemisphere dominance. This study is aimed at comparing the testes and ovary sizes of healthy left-handed girls and boys with those of healthy right-handed children and investigating whether or not lateralization affects the gonads.

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Objectives: Previous studies have shown that gene expressions can be regulated in the hippocampus of rats after seizures induced by kainic acid (KA). The aim of this study was to examine the potential regulatory impact of KA administration on gene expression levels of enzymes responsible for drug metabolism in rat hippocampal tissue.

Materials And Methods: Rats received intraperitoneal injections of KA and saline at a dose of 10 mg/kg.

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Background And Aims: Although aerobic exercises such as cycling and swimming are increasingly being recommended in Duchenne muscular dystrophy (DMD), their effect on gait and balance parameters is unclear. This study was aimed to investigate the effect of cycling training on balance and spatio-temporal gait parameters in children with DMD.

Methods: Ambulant children (age range: 6.

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  • Gadolinium deposition in rat kidneys was studied following single and multiple doses, aiming to see how long it lasts and if there's a link between deposition levels and T1-weighted image intensity.
  • The study involved 70 rats divided into groups receiving varying doses, with assessments made at different time points using imaging and mass spectrometry.
  • Results showed more injections led to higher gadolinium levels, but there was little difference between low and medium doses, and T1 intensity measurement was found to be unreliable for gauging deposition.
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Background: Among patients undergoing percutaneous vascular intervention, contrast-induced nephropathy (CIN) is associated with increased morbidity and mortality. Serum uric acid/albumin ratio (UAR) has emerged as a new marker associated with poor cardiovascular outcomes. We aimed to evaluate the relationship between UAR and CIN occurrence in patients treated for peripheral artery disease.

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Cutaneous ciliated cysts are rare benign lesions most commonly seen in the lower extremities of young female patients. There is still ongoing debate about the origin of these cysts, with the most common theories being Mullerian heterotopia and eccrine gland metaplasia. To further increase the data pool, we present 2 new cutaneous ciliated cyst cases and gathered data about all 67 cases of literature.

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Objective: The study aimed to determine the prevalence of attention deficit hyperactivity disorder (ADHD) in patients with self-limiting epilepsy with centrotemporal spike wave (SeLECTS), as well as the electroclinical features associated with this comorbid condition and the neurocognitive effects using psychometric tests. Additionally, we analysed the electrophysiological findings and neurocognitive status of patients with ADHD to estimate the prevalence of epilepsy and neurocognitive effects in the ADHD population and evaluate their clinical features.

Method: The study included patients diagnosed with SeLECTS and ADHD who were matched for age and gender.

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Objectives: To assess the impact of sarcopenia and vitamin D levels on the severity of lower urinary tract symptoms (LUTS).

Methods: A total of 193 male patients, aged 60 years and above, who visited the geriatric outpatient clinic at Ibn-i Sina Hospital in Ankara, Turkey, between December 2019 and March 2021, were enrolled. Sarcopenia was diagnosed according to the criteria set by the European Working Group on Sarcopenia in Older People.

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Background/aim: Type 1 diabetes mellitus (T1DM) is caused by the autoimmune-mediated destruction of insulin-producing cells (IPCs) and still has no effective cure. Better understanding of the molecular mechanisms involved in the differentiation of embryonic stem cells (ESCs) into IPCs may help us improve the therapeutic strategies for treating T1DM. 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (Pfkfb1-4) are key regulators of glucose metabolism.

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Background: Mini-crush (MC) and T-stenting and small protrusion (TAP) techniques are frequently used, but the long-term comparison of both techniques in patients with complex bifurcation lesions (CBLs) is still a debatable issue. This study sought to retrospectively evaluate the long-term outcomes of MC and TAP techniques in patients with CBLs.

Methods: A total of 271 patients [male: 202 (78.

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