This study investigates the role of plasma lipidomic signatures, particularly lysophosphatidylcholine (LPC) species, as potential biomarkers for adolescent obesity.
A cohort of 103 individuals, divided into overweight/obese and normal weight groups, underwent lipidomic profiling over a median follow-up of 7.1 years, revealing significant associations between specific LPC species and BMI.
The findings highlight alterations in LPC levels in childhood obesity, suggesting their potential use in identifying metabolic profiles and guiding early preventative interventions.