Antibiotic-induced ROS-mediated Fur allosterism contributes to resistance by inhibiting activation of and .

The increasing antibiotic resistance of primarily driven by genetic mutations poses a significant clinical challenge. Although previous research has suggested that antibiotics could induce genetic mutations in , the molecular mechanisms regulating the antibiotic induction remain unclear. In this study, we applied various techniques (e.

Phycocyanin inhibits -induced hyper-proliferation in AGS cells via activation of the ROS/MAPK signaling pathway.

Background: Reactive oxygen species (ROS)-induced oxidative stress (OS) and hyper-proliferation of gastric epithelial cells (GECs) due to (Hp) infection are important mechanisms that lead to gastric carcinoma. Phycocyanin is a marine functional food additive with antioxidant and anti-inflammatory properties.

Methods: The flow cytometry was used to detect the effect of 150 µM phycocyanin intervention on the cell cycle of human gastric adenocarcinoma cell line (AGS) infected with Hp.

Effects of single bond-ion and single bond-diradical form on the stretching vibration of C=N bridging bond in 4,4'-disubstituted benzylidene anilines.

Fifty-seven samples of model compounds, 4,4'-disubstituted benzylidene anilines, p-X-ArCH=NAr-p-Y were synthesized. Their infrared absorption spectra were recorded, and the stretching vibration frequencies νC=N of the C=N bridging bond were determined. New stretching vibration mode was proposed by means of the analysis of the factors affecting νC=N, that is there are mainly three modes in the stretching vibration of C=N bond: (I) polar double bond form C=N, (II) single bond-ion form C(+)-N(-) and (III) single bond-diradical form C-N.