Publications by authors named "Yajing Ning"
Objective: To investigate the application value of computed tomography (CT) value (HU) in the diagnosis and differential diagnosis of pulmonary cryptococcosis (PC) and to construct a prediction model.
Methods: Retrospective analysis of the clinical data of 73 patients who presented with nodular/mass-type occupations on lung CT and confirmed by histopathology in our hospital from January 2019 to May 2022 were divided into PC group (23 patients) and non-PC group (50 patients) according to the pathological findings, and the CT values of each patient's lung lesions were measured. The differences in age, gender, symptoms, lesion involvement in one/both lungs, lung lobe distribution, number of lesions, maximum lesion diameter (cm), lesion margin condition, and CT value results were compared between the two groups.
The presence of bone metastases (BM) in patients with lung cancer is indicative of a worse prognosis. The present study aims to investigate the risk factors associated with BM in patients with lung cancer. Patients with lung cancer admitted to the First Affiliated Hospital of Anhui Medical University between June 2019 and September 2021 were enrolled in this study.
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- Recent research has evaluated the effectiveness of Raman spectroscopy in diagnosing various tumors, but its specific performance for lung cancer remains uncertain.
- A meta-analysis of 14 studies involving 779 patients showed that Raman spectroscopy has a high sensitivity (92%) and specificity (94%) for detecting lung cancer.
- The findings suggest Raman spectroscopy is a promising diagnostic tool, but further large-scale studies are necessary to validate its use, particularly for real-time detection during procedures like bronchoscopy.
Article Synopsis
- The study discusses acute fibrinous and organizing pneumonia (AFOP), a condition described in 2002, with no established standard treatment, and highlights the controversies surrounding the use of steroids and immunosuppressive drugs due to side effects in older patients.
- An 81-year-old female patient with persistent cough and breathlessness was diagnosed with AFOP after ineffective treatment with antibiotics and antifungals, leading to a lung biopsy that confirmed the disease.
- The patient was effectively treated with steroid monotherapy, achieving complete remission without significant complications, suggesting that steroids could be a reliable treatment option for AFOP in older adults.
Hypoxia promotes mitochondrial glutamine metabolism through HIF1α-GDH pathway in human lung cancer cells.
Biochem Biophys Res Commun
January 2017
Drug-resistance is common in human lung cancer therapy. Hypoxia remarkably contributes to drug-resistance in lung cancer but the underlying mechanism remains elusive. Here we demonstrate that hypoxia-induced glutamine metabolism is involved in drug resistance in lung cancer cells.
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