Constructing Physiological Defense Systems against Infectious Disease with Metal-Organic Frameworks: A Review.

The swift and deadly spread of infectious diseases, alongside the rapid advancement of scientific technology in the past several centuries, has led to the invention of various methods for protecting people from infection. In recent years, a class of crystalline porous materials, metal-organic frameworks (MOFs), has shown great potential in constructing defense systems against infectious diseases. This review addresses current approaches to combating infectious diseases through the utilization of MOFs in vaccine development, antiviral and antibacterial treatment, and personal protective equipment (PPE).

Kinetic Study on the Self-Assembly of Au(I)-Thiolate Lamellar Sheets: Preassembled Precursor vs Molecular Precursor.

Molecular self-assembly has played an important role in nanofabrication. Due to the weak driving forces of noncovalent bonds, developing molecular nanoassemblies that have both robust preparation conditions and stable structure is a challenge. In our previous work, we have developed a reversible self-assembly system of Au(I)-thiolate coordination polymer (ATCP) to form colloidal lamellar sheets and demonstrated the high tailorability and stability of their structures, as well as their promising applications in gold nanocluster/nanoparticle fabrication and UV light shielding.

Manipulation of Inorganic Atomic-Layer Networks by Solution-Phase Co-assembly.

Homogeneous 2D lamellar assemblies of Au thiolate coordination polymer (ATCP) were obtained by two-ligand co-assembly. The orbital levels and the bandgap of the 2D Au -S network in the centre of the lamellae can be continuously tuned by means of the capping ligands on both sides, to give a new type of inorganic-organic composite semiconductor, the band structure of which can be easily tuned by low-temperature solution-phase co-assembly. Furthermore, the chemical reactivity of these ATCP co-assemblies also proved to be strongly dependent on the organic substituents, with well-tuneable transformation rates to gold nanoparticles.

Au(I)-thiolate nanostructures fabricated by chemical exfoliation and their transformation to gold nanoparticle assemblies.

Chemical exfoliation method was applied to transform bulky assemblies of Au(I)-3-mercaptopropionate (MPA) coordination polymer (CP) to nanosheets and nanostrings using sodium citrate as an exfoliator. The exfoliation process and the structural characteristics of the Au(I)-MPA nanosheets and nanostrings were fully investigated by transmission electron microscopy, atomic force microscopy, UV-vis absorption spectroscopy, X-ray photoelectron spectroscopy and so on. As the structural rigidity and stability of the obtained Au(I)-MPA nanosheets, they are ideal precursors for fabrication of water soluble gold nanoparticle assemblies through progressive pyrolysis.