Humoral response to SARS-CoV-2 after vaccination and booster effect in patients undergoing dialysis.

Objective: The aim of this study was to determine and evaluate the postvaccination variation in immunoglobulin G (IgG) receptor-binding domain (RBD) produced in non-SARS-CoV-2-infected patients with nephropathy and renal replacement therapy.

Methods: This is a follow-up study of the humoral response to the BNT162b2 messenger ribonucleic acid COVID-19 vaccine in patients with nephropathy, comparing it with itself at different times and with the healthy population.

Results: In patients with nephropathy, a very striking decrease in IgG RBD was observed compared with the healthy population (P<0.