Study on the protective effects of danshen-honghua herb pair (DHHP) on myocardial ischaemia/reperfusion injury (MIRI) and potential mechanisms based on apoptosis and mitochondria.

Context: Danshen, the dried root and rhizome of Bunge (Labiatae) and honghua, the dried flower of L. (Compositae) as the herb pair was used to treat cardiovascular diseases (CVD).

Objective: To study the effects of DHHP on MIRI and mechanisms based on apoptosis and mitochondria.

Investigating the effects and possible mechanisms of danshen- honghua herb pair on acute myocardial ischemia induced by isoproterenol in rats.

Danshen (salvia miltiorrhiza) and honghua(Carthamus tinctorius) were traditional herb pair with promoting blood circulation and removing blood stasis actions, in China. Both were widely used to treat cardiovascular diseases (CVD) for hundreds years, especially shown definite advantage in the treatment of ischemic heart disease (IHD). However, the mechanism of danshen-honghua herb pair (DHHP) in the treatment of IHD was still unclear.

Wanting to maximize the positive and minimize the negative: implications for mixed affective experience in American and Chinese contexts.

Previous studies have demonstrated that European Americans have fewer mixed affective experiences (i.e., are less likely to experience the bad with the good) compared with Chinese.