Inhibitory potency of active metabolites from different polarities of Datura Stramonium seed extracts: GC-MS analysis, biological evaluations, and molecular docking studies.

Datura Stramonium is a well-known and important medicinal plant that is widely used in various medical systems to treat conditions such as asthma, diabetes, and inflammatory diseases. The aim of this study was to prepare extracts of D. stramonium seeds in different solvent polarities for assessing phytochemical potential, in vitro biological activities, and molecular docking studies.

Early management of presbycusis: recommendations from the French Society of Otorhinolaryngology and Head and Neck Surgery, the French Society of Audiology, and the French Society of Geriatrics and Gerontology.

Introduction: Presbycusis is the physiological decrease in hearing due to advancing age and begins well before the sixth decade. These recommendations recall the principles of early diagnosis of presbycusis and the means of optimal rehabilitation as soon as the first symptoms appear.

Material And Methods: The recommendations are based on a systematic analysis of the literature carried out by a multidisciplinary group of ENT physicians, audiologists, geriatricians and hearing specialists from all over France.

[Early management of presbycusis: recommendations from the French Society of Otorhinolaryngology and Head and Neck Surgery, the French Society of Audiology, and the French Society of Geriatrics and Gerontology].

Introduction: Presbycusis is the physiological decrease in hearing due to advancing age and begins well before the sixth decade. These recommendations recall the principles of early diagnosis of presbycusis and the means of optimal rehabilitation as soon as the first symptoms appear.

Material And Methods: The recommendations are based on a systematic analysis of the literature carried out by a multidisciplinary group of doctors and audioprosthetists from all over France.

Robotized Cochlear Implantation under Fluoroscopy: A Preliminary Series.

It is known that visual feedback by fluoroscopy can detect electrode array (EA) misrouting within the cochlea while robotized EA-insertion (rob-EAI) permits atraumatic cochlear implantation. We report here our unique experience of both fluoroscopy feedback and rob-EAI in cochlear implant surgery. We retrospectively analyzed a cohort of consecutive patients implanted from November 2021−October 2022 using rob-EAI, with the RobOtol®, to determine the quality of EA-insertion and the additional time required.

Control of non-conformities in the pre-analytical phase at the Bacteriology Laboratory of the Ibn Sina University Hospital in Rabat (Morocco).

Introduction: The errors in the pre-analytic phase are at the origin of 60 to 85% of the errors in the results proceeded from laboratory.

Aim: To evaluate the impact of the pre-analytical phase on the received bacteriology samples received at the medical bacteriology laboratory of Ibn Sina UH in Rabat Morocco in order to propose corrective actions.

Methods: A descriptive and quantitative study of the non-conformities of the pre-analytical phase identified in the central laboratory of medical bacteriology of the Ibn Sina hospital in Rabat over a period of 6 months (from January 01 to July 01, 2020).

Poor dental condition is a factor of imbalance of the nutritional status at the outset of management of head and neck cancer.

Objectives: To determine whether deterioration of dental condition at the outset of management of head and neck cancer (HNC) is a nutritional risk and whether social deprivation is a cause of the poor dental condition observed in HNC patients.

Material And Methods: A nutritional assessment form (NAF) and the Nutrition Risk Index (NRI) were used to standardize the nutritional status of 108 patients at the outset of management of HNC (2017-2019). The NAF includes assessment of weight loss over the past 3 months, the amount and difficulty of food intake, and the presence of digestive disorders.

Management of biological and infectious risks at the medical bacteriology Laboratory of the Ibn Sina University Hospital in Rabat.

Introduction: The laboratory of bacteriology is a place with a potential risk and permanent exhibition to biological and infectious hazards caused by the handling of potentially contaminated biological products.

Aims: To evaluate biological and infectious, analyze the circumstances of incidents and accidents and propose a professional risk assessment process (EvRP) to the laboratory with an action plan that can be carried out immediately.

Methods: A descriptive epidemiological cross-sectional study carried out in the medical bacteriology laboratory of the Ibn Sina University Hospital in Rabat over a period of twelve months.

Chemical Composition, Antimicrobial activity, in Vitro Cytotoxicity and Leukotoxin Neutralization of Essential Oil from against .

In this study, the essential oil of was evaluated for putative antibacterial activity against six clinical strains and five reference strains of , in comparison with some antimicrobials. The chemical composition of the essential oil was analyzed, using chromatography (CG) and gas chromatography-mass spectrometry coupled (CG-MS). The major compounds in the oil were Carvacrol (32.

[Quality of blood salvaged in orthopedic surgery by washing swabs].

Objective: To establish the feasibility and safety of recuperating blood absorbed by swabs used during orthopaedic surgery.

Study Design: Open, prospective study.

Patients: Included were children undergoing potentially haemorrhagic orthopaedic surgery for whom intraoperative blood salvage seemed possible.

[False hydatic aneurysm of the thoraco-abdominal aorta].

Arterial complications of hydatic disease are rarely encountered. We report a false hydatic aneurysm of the thoracoabdominal aorta revealed by ischemic embolism of the lower limbs. Surgical treatment included aorto-aortic prosthesis and albendazol for 6 months.

Viability of keratocytes in epikeratophakia lenticules.

Aim: To study the influence of cryoprotectant, cooling rate, and warming rate on recovery and viability of keratocytes from corneas for cryolathing.

Methods: Corneas were frozen at -50 degrees C for 2 minutes either after exposure to 10% dimethyl sulphoxide in Eagle's MEM for 15 minutes at room temperature (about 22 degrees C), or without earlier exposure to the cryoprotectant. Corneas were cooled either rapidly (20 degrees C/min) or slowly (1 degree C/min), and they were warmed either rapidly (> 50 degrees C/min) by direct transfer into medium at 22 degrees C or slowly (< 20 degrees C/min) in air at 22 degrees C.

Effects of irrigation solutions on corneal endothelial function.

Rabbit corneas were perfused in vitro with an irrigation solution for 90 minutes. This was followed by 6 hours of perfusion with tissue culture medium TC199 during which endothelial function was assessed by monitoring rates of swelling during a period of perfusion in the absence of bicarbonate ions, and subsequent rates of thinning when bicarbonate ions were restored to the perfusate. Corneal thickness (measured with an ultrasonic pachymeter) immediately following excision was 401 microns (SD 19, n = 23).