Non-classical 21-hydroxylase deficiency: prevalence in males with unexplained abnormal sperm analysis.

Objective: To evaluate the prevalence of nonclassical 21-hydroxylase deficiency (NC-21OHD) in men with abnormal sperm parameters of unexplained etiology compared with males with normal sperm analysis.

Design: Case control study.

Setting: Major tertiary medical center.

Childhood obesity complicating the differential diagnosis of maturity-onset diabetes of the young and type 2 diabetes.

Objective: To describe a proband with features of type 2 diabetes who was found to have concomitant maturity-onset diabetes of the young (MODY) and the consequent multigeneration genetic analysis.

Design: Familial genetic analysis.

Setting: Tertiary university medical center.

Decreased growth during therapy with selective serotonin reuptake inhibitors.

Background: There is no information on the effects of selective serotonin reuptake inhibitors (SSRIs) on growth and puberty in children. We examined growth and growth hormone secretion in 4 children treated with SSRIs for various psychiatric disorders.

Design: Case study.