Okazaki fragment maturation: DNA flap dynamics for cell proliferation and survival.

Unsuccessful processing of Okazaki fragments leads to the accumulation of DNA breaks which are associated with many human diseases including cancer and neurodegenerative disorders. Recently, Okazaki fragment maturation (OFM) has received renewed attention regarding how unprocessed Okazaki fragments are sensed and repaired, and how inappropriate OFM impacts on genome stability and cell viability, especially in cancer cells. We provide an overview of the highly efficient and faithful canonical OFM pathways and their regulation of genomic integrity and cell survival.

Google analytics of a pilot study to characterize the visitor website statistics and implicate for enrollment strategies in Medical University.

Background: Taiwan's colleges and universities are struggling to maintain their student enrollment rates owing to the declining fertility rate. Focusing on students in higher education programs, this study aims to analyze online behavioral patterns for university departmental websites and accordingly, suggests response strategies to increase the rate of enrollment.

Methods: We use Google Analytics to examine the websites of two departments in a medical university between February 1 and July 30, 2018.

Correlation between Gout and Coronary Heart Disease in Taiwan: A Nationwide Population-Based Cohort Study.

Background: Gout is the most common inflammatory arthritis in adult males. Patients with gout are at a higher risk of coronary heart disease (CHD). This study aimed to investigate the correlation between gout and CHD.

Prescribing Trend of Antirheumatic Drugs in Taiwan and Risk of Cardiovascular Disease in Patients with Rheumatoid Arthritis: A Nationwide Cohort Study.

We aimed to investigate the prescribing trend of antirheumatic drugs and assess the risk of cardiovascular disease in patients with rheumatoid arthritis in Taiwan. This study was a retrospective cohort study, conducted based on the Taiwan National Health Insurance Research Database. The study subjects were 15,366 new rheumatoid arthritis patients from 2003 to 2010.

Correlation between diabetes mellitus and periodontitis in Taiwan: A nationwide cohort study.

Aims: The mechanism underlying the association of diabetes mellitus (DM) and periodontitis is not clear. This study aimed to investigate the correlation between DM and periodontitis.

Methods: This study was a retrospective cohort study, which conducted based on the Taiwan National Health Insurance Research Database.

Identifying competitive strategies to improve the performance of hospitals in a competitive environment.

Background: This study is based on competitive dynamics theory, and discusses competitive actions (including their implementation requirements, strategic orientation, and action complexity) that influence hospitals' performance, while also meeting the requirements of Taiwan's "global budget" insurance payment policy.

Methods: In order to investigate the possible actions of hospitals, the study was conducted in two stages. The first stage investigated the actions of hospitals from March 1 to May 31, 2009.

Increased low back pain risk in nurses with high workload for patient care: A questionnaire survey.

Objective: To examine whether the prevalence of low back pain (LBP) increased in hospital nurses with high patient care workload.

Materials And Methods: A structured, self-administered questionnaire was used to collect information on the prevalence of LBP and its associated factors from 788 registered nurses from a medical center in Taiwan.

Results: Among all nurses with eligible questionnaires, 567 (72.

Learning organizations, internal marketing, and organizational commitment in hospitals.

Background: Knowledge capital is becoming more important to healthcare establishments, especially for hospitals that are facing changing societal and industrial patterns. Hospital staff must engage in a process of continual learning to improve their healthcare skills and provide a superior service to their patients. Internal marketing helps hospital administrators to improve the quality of service provided by nursing staff to their patients and allows hospitals to build a learning culture and enhance the organizational commitment of its nursing staff.

Using internal marketing to improve organizational commitment and service quality.

Aim: The purpose of this article was to explore the structural relationships among internal marketing, organizational commitment and service quality and to practically apply the findings.

Background: Internal marketing is a way to assist hospitals in improving the quality of the services that they provide while executing highly labour-intensive tasks. Through internal marketing, a hospital can enhance the organizational commitment of its employees to attain higher service quality.

Relationship between organizational culture, leadership behavior and job satisfaction.

Background: Organizational culture refers to the beliefs and values that have existed in an organization for a long time, and to the beliefs of the staff and the foreseen value of their work that will influence their attitudes and behavior. Administrators usually adjust their leadership behavior to accomplish the mission of the organization, and this could influence the employees' job satisfaction. It is therefore essential to understand the relationship between organizational culture, leadership behavior and job satisfaction of employees.

The relationships between organisational citizenship behaviour, job satisfaction and turnover intention.

Aim: This study aims to explore the relationships between organisational citizenship behaviour, job satisfaction and turnover intention.

Background: Because of the changing health policies landscape, Taiwan's hospital administrators are facing major cost reduction challenges. Specifically, the high turnover rate of nurses represents a hindrance and a human resource cost.