Safety of vaginal breech delivery following an unsuccessful external cephalic version: a comparative study.

Objective: To determine whether patients undergoing a trial of labor with a breech presentation following a failed attempt of external cephalic version (ECV) are at increased risk of adverse maternal and neonatal outcomes.

Methods: This retrospective cohort study was conducted at a single university-affiliated medical center. The study group comprised women with singleton pregnancies at term, categorized into three groups: those who underwent a failed external cephalic version (ECV) and subsequently attempted a trial of breech delivery (Breech-failed-ECV group), those who attempted an assisted vaginal breech delivery without a prior ECV attempt (Breech-no-ECV group), and those with vertex presentation following a successful ECV (Vertex-ECV).

Long-term follow-up of congenital anomalies of the kidney and urinary tract diagnosed in utero: a longitudinal study.

Background: Congenital-anomalies of the kidney-and-urinary-tract (CAKUT) are diagnosed in 3-6 per 1000 live-births. The objective of the current study was to examine the short and long-term outcomes of children diagnosed prenatally with CAKUT.

Methods: A retrospective study was performed in 2018 on all pregnancies diagnosed with CAKUT between 2004 and 2008 at our hospital.

Enhanced expression of Galectin-3 in gestational diabetes.

Background And Aims: Gestational diabetes mellitus (GDM), hyperglycemia diagnosed during pregnancy, is one of the most common medical complications of pregnancy, treated primarily by diet and pharmacotherapy, if indicated. It is well-established that GDM increases the risk of adverse pregnancy outcomes and long-term complications in mothers and infants. Galectin-3 (Gal-3) is important in processes of cell growth, differentiation, inflammation, and fibrosis.

Diagnostic accuracy of random urinary protein-to-creatinine ratio for proteinuria in patients with suspected pre-eclampsia.

Purpose: To evaluate the correlation between urine protein/creatinine ratio (UPCR) and proteinuria in a 24-h urine collection and to calculate the predicative accuracy of different cutoffs of UPCR for the diagnosis of proteinuria.

Methods: A retrospective cohort study including women who admitted for the evaluation for suspected preeclampsia (PET) beyond 20 weeks of gestation in a single tertiary center. Both UPCR test and quantification of proteinuria using 24-h urine collection were obtained during their index hospitalization no more than 48 h apart.

The Risk of Preterm Birth in Women with Three Consecutive Deliveries-The Effect of Number and Type of Prior Preterm Births.

We aimed to explore the association of the number, order, gestational age and type of prior PTB and the risk of preterm birth (PTB) in the third delivery in women who had three consecutive singleton deliveries. A retrospective cohort study of all women who had three consecutive singleton births at a single medical center over a 20-year period (1994-2013). The primary outcome was PTB (<37 weeks) in the third delivery.

Gestational Diabetes Type 2: Variation in High-Density Lipoproteins Composition and Function.

Class A2 gestational diabetes mellitus (GDMA2) has short- and long-term effects on the mother and child. These may include abnormalities of placentation, damage to endothelial cells and cardiovascular disease. This research investigated the function and composition of high-density lipoproteins (HDL) among women with GDMA2 and their fetuses.

The yield of chromosomal microarray testing for cases of abnormal fetal head circumference.

Objectives: Chromosomal microarray analysis (CMA) is the method of choice for genetic work-up in cases of fetal malformations. We assessed the detection rate of CMA in cases of abnormal fetal head circumference (HC).

Methods: The study cohort was based on 81 cases of amniocenteses performed throughout Israel for the indication of microcephaly (53) or macrocephaly (28), from January 2015 through December 2018.

The possibility of integrating motile sperm organelle morphology examination (MSOME) with intracytoplasmic morphologically-selected sperm injection (IMSI) when treating couples with unexplained infertility.

Purpose: To examine the efficacy of motile sperm organelle morphology examination (MSOME) and intracytoplasmic morphologically-selected sperm injection (IMSI) for unexplained infertility.

Methods: This historical study, included 271 couples with primary, unexplained infertility/male subfertility, treated at an outpatient, IVF clinic, 2015-2018. These couples underwent MSOME after ≥3 failed intrauterine insemination (IUI) cycles and ≥1 failed IVF-ICSI cycle.

The yield of chromosomal microarray analysis among pregnancies terminated due to fetal malformations.

Background: Chromosomal microarray analysis (CMA) is preferred for genetic work-up when fetal malformations are detected prenatally.

Objectives: To assess the detection rate of CMA after pregnancy termination due to abnormal ultrasound findings.

Methods: CMA was successfully performed in 71 pregnancies using fetal DNA (mainly from skin) or placenta.

Thioredoxin, thioredoxin interacting protein and transducer and activator of transcription 3 in gestational diabetes.

To evaluate changes in the inflammatory response of thioredoxin (TXN), thioredoxin interacting protein (TXNIP), transducer and activator of transcription 3, NFƙB-p50 and STAT3 at the level of maternal serum, placenta, and umbilical cord blood of women with gestational diabetes mellitus type 2 (GDMA2) compared to normal pregnancies (NP). Thirty pregnant women (20 with GDMA2 and 10 NP) were recruited during admission for delivery. Blood samples were obtained from the parturients and umbilical cords, as well as placental tissue for mRNA and protein extraction.

Does music during labor affect mode of delivery in first labor after epidural anesthesia? A prospective study.

Key Message: Listening to music during labor increases the likelihood that primiparas will have a spontaneous vaginal delivery.

Purpose: To examine the effects of exposure to music during labor on the mode of delivery and parturients' stress levels.

Methods: This prospective, interventional study included 124 low-risk women who were recruited during latent phase of their first labor after epidural anesthesia.

Physiological and psychological stress responses to labor and delivery as expressed by salivary cortisol: a prospective study.

Background: Labor is considered a stressful event, yet no study has described the course of stress measured by cortisol during labor and postpartum.

Objective: The objective of the study was to describe the patterns of physiological and psychological stress during labor as measured by salivary cortisol concentrations and stress questionnaires and their correlation to obstetric and neonatal outcomes.

Study Design: This prospective, observational study included 167 women with low-risk, singleton, term deliveries at a tertiary academic center.

Does stress affect IVF outcomes? A prospective study of physiological and psychological stress in women undergoing IVF.

Research Question: What are the effects of physiological and psychological stress on fertility outcomes for women undergoing IVF?

Design: A prospective cohort study of 72 patients undergoing IVF in 2017 and 2018. Physiological stress was assessed by salivary cortisol measurements: (i) pretreatment, when the patient received the IVF protocol; (ii) before oocyte retrieval (follicular cortisol was also measured); and (iii) before embryo transfer. Emotional stress was evaluated at each assessment with the State-Trait Anxiety Inventory and a 1-10 Visual Analogue Scale (VAS, referred to as the 'Stress Scale'.

Labor progression of women attempting vaginal birth after previous cesarean delivery with or without epidural analgesia.

Purpose: Normal labor curves have not been assessed for women undergoing a trial of labor after cesarean delivery (TOLAC). This study examined labor patterns during TOLAC in relation to epidural analgesia use.

Methods: Retrospective cohort study of deliveries of women undergoing TOLAC at a single, academic, tertiary medical center.

Perinatal outcomes of unplanned out-of-hospital deliveries: a case-control study.

Purpose: To compare the pregnancy and perinatal outcomes of unplanned home or car births vs. in-hospital deliveries.

Methods: A retrospective, case-control study of women who underwent unplanned out-of-hospital deliveries vs.

Fertility outcomes after extended searches for ejaculated spermatozoa in men with virtual azoospermia.

Objective: To assess the fertility outcomes of extended searches for ejaculated spermatozoa in men with virtual azoospermia.

Design: A retrospective cohort of 242 couples whose male partner suffered from nonobstructive azoospermia and who were treated with the use of intracytoplasmic sperm injection (ICSI).

Setting: Not applicable.

Skin closure at cesarean delivery, glue vs subcuticular sutures: a randomized controlled trial.

Background: The optimal choice of skin closure at cesarean delivery has not yet been determined.

Objective: This study compared wound complications and scar healing following cesarean delivery between 2 methods of skin closure: glue (Dermabond; Ethicon, Somerville, NJ) and monofilament (Monocryl; Ethicon) epidermal sutures.

Study Design: We conducted a randomized controlled trial in which pregnant women undergoing a scheduled cesarean delivery were randomly assigned to skin (epidermis) closure with glue or with a monofilament synthetic suture.

Predictors of twin pregnancy after ovarian stimulation and intrauterine insemination in women with unexplained infertility.

Multi-foetal gestation is a well-known, adverse outcome of infertility treatment. Maternal and obstetrical complications are more frequent in multiple pregnancies compared to singletons. The aim of this study was to determine parameters that affect the risk for multiple pregnancies after ovarian stimulation (OS) with intrauterine insemination (IUI).

Maternal nutrition and offspring's adulthood NCD's: a review.

Overnutrition and undernutrition during pregnancy are closely related to pregnancy outcome as well as neonatal and perinatal outcomes. This and more, from various published data it seems that the effect of maternal nutrition during fetal life stretches far beyond the neonatal period, and influences health issues in adulthood, from cardiovascular and metabolic disorders through mental illnesses. The purpose of this review is to update about overnutrition and undernutrition during pregnancy and their effect on noncommunicable adulthood diseases, and about leading theories on the subject.

Obstetric and perinatal outcomes in women with eating disorders.

Background: We wished to investigate whether women with a history of eating disorders have an increased risk for adverse obstetric and perinatal outcomes.

Study Design: A retrospective study was conducted comparing pregnancy complications in patients with and without eating disorders. Deliveries occurred during the years 1988-2009 in a tertiary medical center.