Publications by authors named "Yael Bublil Lavi"
Coronavirus disease 2019 (COVID-19) presents a wide spectrum of symptoms, the causes of which remain poorly understood. This study explored the associations between autoantibodies (AABs), particularly those targeting G protein-coupled receptors (GPCRs) and renin‒angiotensin system (RAS) molecules, and the clinical manifestations of COVID-19. Using a cross-sectional analysis of 244 individuals, we applied multivariate analysis of variance, principal component analysis, and multinomial regression to examine the relationships between AAB levels and key symptoms.
View Article and Find Full Text PDFAge is a significant risk factor for the coronavirus disease 2019 (COVID-19) severity due to immunosenescence and certain age-dependent medical conditions (e.g., obesity, cardiovascular disorder, and chronic respiratory disease).
View Article and Find Full Text PDFArticle Synopsis
- COVID-19 is linked to the production of autoantibodies, similar to systemic autoimmune diseases, indicating their role in the disease's severity.
- A study of 246 individuals revealed that higher levels of autoantibodies targeting G protein-coupled receptors (GPCR) and RAS-related molecules correlate with more severe cases of COVID-19.
- Specific autoantibodies, particularly against the receptors CXCR3 and AGTR1, were identified as having the strongest association with the severity of the disease, suggesting that changes in their levels and patterns could potentially predict COVID-19 outcomes.