Publications by authors named "Yae Hasegawa"
Article Synopsis
- Babesiosis can significantly harm immunocompromised individuals, and this study explored immune responses during acute co-infection using a mouse model.
- Primary infections helped mitigate parasitemia by boosting specific immune responses early on, but co-infection weakened the splenic immune function, reducing critical B and T cells.
- Cytokine analysis revealed that pro-inflammatory cytokines were downregulated while anti-inflammatory IL-10 increased, and differences in serum cytokine levels highlighted how timing of infection can influence disease severity.
Diseases caused by tick-transmitted pathogens including bacteria, viruses, and protozoa are of veterinary and medical importance, especially in tropical and subtropical regions including Turkey. Hence, molecular surveillance of tick-borne diseases will improve the understanding of their distribution towards effective control. This study aimed to investigate the presence and perform molecular characterization of Babesia sp.
View Article and Find Full Text PDFBackground: Drug resistance and toxic side effects are major challenges in the treatment of babesiosis. As such, new drugs are needed to combat the emergence of drug resistance in Babesia parasites and to develop alternative treatment strategies. A combination of naphthoquine (NQ) and artemisinin is an antimalarial therapy in pharmaceutical markets.
View Article and Find Full Text PDFTick-borne diseases (TBDs) considerably impair equine health and productivity. Moreover, TBDs, particularly equine piroplasmosis, impede international movement and trade of equids, which is a vital component of the global horse racing industry. In the Philippines, horse racing is a lucrative industry generating millions of USD annually.
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