Sub-minimum inhibitory concentrations in ceftazidime exacerbate the formation of Acinetobacter baumannii biofilms.

Associated with nosocomial infections, the environmental Gram-negative coccobacillus A. baumannii leads to various kinds of high mortality-rate infections among which pneumonias mainly in immune-compromised people from health-care facilities. A critical component of the current antibiotic resistance problem is the presence of antibiotics sub-minimum inhibitory concentrations (sub-MICs) in a variety of natural settings including drinking water, sewage water, rivers, lakes, and natural sludge.

Evaluation of anthracycline-induced cardiotoxicity using cardiac biomarkers: A prospective study.

Background: Though anthracyclines are the commonly used chemotherapeutics for cancer treatment, close monitoring of patients is required due to its well reported cardiotoxicity. The present study evaluates the role of biomarkers [N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high sensitivity cardiac troponin-T (hs-cTnT)] in early prediction of cardiotoxicity in patients with breast and ovarian cancer who received anthracyclines.

Methods: This was a single-center observational study conducted between August-2018 and January-2020.

Sensing behavior of CdS-TiO thick films for the detection of hydrocarbons.

In this article, the sensing behaviors of undoped titanium dioxide (TiO) and CdS-doped TiO (CdS-TiO) thick films are discussed. Sensing pastes of 2 wt% CdS-TiO and undoped TiO were prepared in the laboratory and used to fabricate thick film gas sensors on an alumina substrate. The crystal structures of TiO and CdS-TiO samples were characterized by XRD and atomic force microscopy (AFM).

Evaluating the Research Productivity in Pulpotomy: A Bibliometric Analysis.

The aim of this study was to appraise the bibliometric parameters of pulpotomy in the past 24 years from January 2000 to December 2023. The dataset was obtained from the Web of Science (WoS) database. The filter publication years were applied.

Potential health, environmental implication of microplastics: A review on its detection.

Microplastic contamination of terrestrial and aquatic environment has gained immense research attention due to their potential ecotoxicity and biomagnification property when enterer into food chain. Heterogenous nature of microplastics coupled with their ability to combine with other emerging pollutants have increased the severity of this crisis. Existing detection methods often fails to accurately quantify the amount of microplastic components present in environmental and biological samples.

A state-of-the-art review on the quantitative and qualitative assessment of water resources using google earth engine.

Water resource management is becoming essential due to many anthropogenic and climatic factors resulting in dwindling water resources. Traditionally, geographic information systems (GIS) and remote sensing (RS) have long been instrumental in water resource assessment and management as the satellites or airborne units are periodically utilized to collect data from large areal extent. However, these platforms have limited computational capability and localized storage systems.

LPG Sensing Study of Calcium-Doped Praseodymium Orthoferrite Nanomaterial.

Liquefied petroleum gas (LPG) is a modern fuel for kitchens, vehicles, and industry. Leakage of LPG is extremely fatal for humans and the atmosphere; therefore, quick detection is a vital need. The sol-gel self-combustion process was applied to synthesize the calcium-doped praseodymium orthoferrite (PrFeO) nanomaterials.

Orbital hematoma due to vitamin K deficiency in an infant.

We report a rare case of late-onset vitamin K deficiency bleeding in a 3-month-old boy who presented with orbital compartment syndrome due to massive bleed in the right orbit. The coagulation profile was highly abnormal. The patient was treated with vitamin K injections, following which the coagulation profile normalized.

Individualised Lifestyle Intervention in Polycystic Ovarian Syndrome Women Who Desire Fertility: A Feasibility Study.

Background: Polycystic ovarian syndrome (PCOS) is one of the common causes of anovulatory infertility among women in the reproductive age group. Women with PCOS and obesity often have difficulty in conceiving, and they are more prone for developing metabolic syndrome. Lifestyle modification plays a key role in women with PCOS, who are overweight or obese and is recommended as a first line management option.

"Behavioural and metabolic risk factors of cardiovascular diseases among post-menopausal women: A cross-sectional study in Itahari sub-metropolitan city of Nepal".

Background And Objectives: Cardiovascular diseases (CVDs) are main cause of mortality and morbidity among women globally. Menopause, aging and different factors in collaboration leads to increased risk for CVDs among postmenopausal women but study on risk factors of CVDs among postmenopausal women is limited in Nepal. Therefore, we aimed to assess prevalence of behavioural and metabolic risk factors of cardiovascular disease among post-menopausal women.

Impact of 5-Flurouracil loaded chitosan nanoparticle on A375 and A431 cell line for the therapy of skin cancer.

Skin cancer is an uncontrolled proliferation of abnormal skin cells that is usually caused by damaging UV radiation. Skin cancer is classified into two types: non-melanoma skin cancer and melanoma skin cancer. The entire studies focus on cytotoxic effect of prepared 5-Flurouracil loaded chitosan nanoparticle using A375 and A431 skin cancer cell line.

Impact of antral follicle count on follicular-luteal characteristics, superovulatory response, and embryo quality in Sahiwal cows.

The study aimed to evaluate the effect of antral follicle count (AFC) on follicular and luteal development during the estrous cycle and superovulatory period, as well as on superovulatory response and embryo quality within the MOET program. A total of 48 estrus-induced (500 μg PGF2α, Single dose, IM) Sahiwal cows () with a BCS between 3.5 and 4.

Stretchable hierarchical metal wire networks for neuromorphic emulation of nociception and anti-nociception.

Among biomimetic technologies, the incorporation of sensory hardware holds exceptional utility in human-machine interfacing. In this context, devices receptive to nociception and emulating antinociception gain significance as part of pain management. Here we report, a stretchable two-terminal resistive neuromorphic device consisting of a hierarchical Ag microwire network formed using a crack templating protocol.

Treatment of electrographic seizures versus clinical seizures in neonates: A systematic review and meta-analysis.

Introduction: Electrographic seizures in neonates are commonly associated with poor neurodevelopmental outcomes. However, there is conflict in evidence whether control of electrographic seizures translate into improved neurodevelopmental outcome. We aimed to evaluate whether treating all electrographic seizures compared with treating clinical seizures leads to a better neurodevelopmental outcome at 18-24 months in neonates.

Unravelling the stabilization mechanism of mono-, di- and tri-cholinium citrate-ethylene glycol DESs towards α-chymotrypsin for preservation and activation of the enzyme.

Deep eutectic solvents (DESs) are considered as designer solvents that serve as alternatives to traditional solvents. Numerous favourable properties and advantageous characteristics promote their utility in bio-catalysis. Therefore, they have emerged as attractive sustainable media for different biomacromolecules.

Sustainable innovations and future prospects in construction material: a review on natural fiber-reinforced cement composites.

There is a growing trend in the construction industry to adopt environmentally friendly practices, and innovative materials are becoming increasingly popular. Within the scope of this paper, the potential of natural fiber-reinforced cement composites (NFRCs) as an environmentally friendly building material is examined. This work introduces plant fiber aspects such as micromorphology, primary components, physical and mechanical properties, chemical components, thermal properties, and degradation mechanisms in cement composites.

Enhancing local-scale groundwater quality predictions using advanced machine learning approaches.

Assessing groundwater quality typically involves labor-intensive, time-consuming, and costly laboratory tests, making real-time monitoring impractical, especially at the local level. Groundwater quality projections at the local scale using broad spatial datasets have been inaccurate due to variations in hydrogeology, human activities, industrial operations, groundwater extraction, and waste disposal. This study aims to identify the most dependable and resilient machine learning algorithms for forecasting groundwater quality at nearby monitoring locations by utilizing simple water quality metrics that can be quickly assessed without extensive sampling and laboratory testing.

Association of Donor Vascular Endothelial Growth Factor Gene Polymorphism With Acute Renal Allograft Rejection.

Background: Recipient's VEGF-A polymorphisms have been reported to be associated with the risk of acute allograft rejection. However, an association of the donor's VEGF-A gene polymorphism with rejection remained unelucidated till now.

Methods: In this study, VEGF-A gene SNPs at nine loci were analyzed in 160 kidney donors and recipients with rejection (rejectors, n = 80) and without rejection (non-rejectors, n = 80).

Sub-acute bisphenol A exposure induces proteomic alterations and impairs male reproductive health in mice.

Bisphenol A (BPA) is one of the most prevalent endocrine disrupting chemicals (EDCs) and there is widespread concern about the adverse effects of EDCs on human health. However, the exact mechanism of these toxicities has still not been fully deciphered. Additionally, studies have reported the toxicological effects at far low doses to the generally considered no-observed-adverse-effect level (NOAEL) dose.

Ayurvedic Management of Presbycusis (Project TOPMAC): Protocol for an Exploratory Randomized Controlled Trial.

Background: Presbycusis is characterized by sensorineural hearing loss in both ears at high frequencies, which affects more than half of the older adults by the age of 75 years and is often accompanied by tinnitus and cognitive deterioration. Unfortunately, there are no treatments available to restore hearing loss. Treatment mainly focuses on improving the quality of life and communication with hearing aids.

Exposure to Various Degrees and Durations of Hypobaric Hypoxia Causes a Reduction in Body Weight of Female Adult Rats.

Background: Hypobaric hypoxia refers to a condition where there is a decreased oxygen partial pressure in the air due to low atmospheric pressure. It is known to affect the metabolism, leading to increased basal metabolic rate, alterations in appetite, and changes in cellular metabolism and energy homeostasis. The effects of hypoxia on metabolism and weight loss are influenced by genetic factors, gender, and the duration and severity of exposure to hypoxia.

Comparative efficacies of vitamin D supplementation regimens in infants: a systematic review and network meta-analysis.

Vitamin D deficiency in infants is widely prevalent. Most paediatric professional associations recommend routine vitamin D prophylaxis for infants. However, the optimal dose and duration of supplementation are still debated.